ArticleJournal of perinatology : official journal of the California Perinatal Association2019
Early onset sepsis calculator-based management of newborns exposed to maternal intrapartum fever: a cost benefit analysis.
Article in Journal of perinatology : official journal of the California Perinatal Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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Who cites it
9 citing papers in PubMed.
- Implementation of the early-onset sepsis calculator in a tertiary care NICU.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2026Article
- Clinical Outcomes of the Adapted AAP 2019 Guidelines on Early Onset Sepsis in Thailand.Antibiotics (Basel, Switzerland) · 2025Article
- Clinical and economic impacts of a modified-observational screening approach to well-appearing infants born to mothers with chorioamnionitis.Journal of perinatology : official journal of the California Perinatal Association · 2024Article
- Barriers and Facilitators to the Implementation of the Early-Onset Sepsis Calculator: A Multicenter Survey Study.Children (Basel, Switzerland) · 2023Article
- Efficacy of continuous monitoring of maternal temperature during labor using wireless axillary sensors.Journal of clinical monitoring and computing · 2022Article
- Early-onset sepsis risk calculator: a review of its effectiveness and comparative study with our evidence-based local guidelines.Italian journal of pediatrics · 2021Article
- Multivariate risk and clinical signs evaluations for early-onset sepsis on late preterm and term newborns and their economic impact.European journal of pediatrics · 2020Article
- Early onset sepsis calculator implementation is associated with reduced healthcare utilization and financial costs in late preterm and term newborns.European journal of pediatrics · 2020Article
- Resource Utilization and Costs Associated with Approaches to Identify Infants with Early-Onset Sepsis.MDM policy & practiceArticle
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo determine potential net monetary benefit of an early onset sepsis calculator-based approach for management of neonates exposed to maternal intrapartum fever, compared to existing guidelines. STUDY
designWe performed a cost-benefit analysis comparing two management approaches for newborns >34 weeks gestational age exposed to maternal intrapartum fever. Probabilities of sepsis and meningitis, consequences of infection and antibiotic use, direct medical costs, and indirect costs for long-term disability and mortality were considered.
resultsA calculator-based approach resulted in a net monetary benefit of $3998 per infant with a 60% likelihood of net benefit in probabilistic sensitivity analysis. Our model predicted a 67% decrease in antibiotic use in the calculator arm. The absolute difference for all adverse clinical outcomes between approaches was ≤0.6%.
conclusionsCompared to existing guidelines, a calculator-based approach for newborns exposed to maternal intrapartum fever yields a robust net monetary benefit, largely by preventing unnecessary antibiotic treatment.
Indexed as
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30692615What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.