Evidence map›Paper›PMID 30692613›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2019

Neuroimaging and Bayley-III correlates of early hand function in extremely preterm children.

Andrea F Duncan, Carla M Bann, Allison G Dempsey, Ira Adams-Chapman, Roy Heyne, Susan R Hintz, Eunice Kennedy Shriver National Institute of Child Health and Development Neonatal Research Network

Abstract read
In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Andrea F DuncanDepartment of Pediatrics, Division of Neonatal-Perinatal Medicine, University of Texas Health Science Center at Houston, Houston, TX, USA. Andrea.F.Duncan@uth.tmc.edu.
Carla M BannStatistics and Epidemiology Unit, RTI International, Research Triangle Park, NC, USA.
Allison G DempseyDepartment of Pediatrics, Division of Neonatal-Perinatal Medicine, University of Texas Health Science Center at Houston, Houston, TX, USA.
Ira Adams-ChapmanDepartment of Pediatrics, Division of Neonatal-Perinatal Medicine, Emory University, Atlanta, GA, USA.
Roy HeyneDepartment of Pediatrics, Division of Neonatal-Perinatal Medicine, University of Texas Southwestern Medical Center at Dallas, Dallas, TX, USA.
Susan R HintzDepartment of Pediatrics, Division of Neonatal-Perinatal Medicine, Stanford University, Palo Alto, CA, USA.
Eunice Kennedy Shriver National Institute of Child Health and Development Neonatal Research Network

Funding

NICHD Cooperative Multicenter Neonatal Research NetworkU10HD021373 · NICHD · UNIVERSITY OF TEXAS SW MED CTR/DALLAS · PI KENNEDY, KATHLEEN A · 1991 to 2015
$6.1M
NICHD Cooperative Multicenter Neonatal Research Network - Utah CenterUG1HD087226 · NICHD · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI ROBIN K OHLS · 2016 to 2026
$3.3M
NICHD NIH HHS U10 HD021373NICHD NIH HHS UG1 HD087226
6 · The paper itself

Abstract

OBJECTIVE(S): Investigate associations between 18 and 22-month corrected age hand function, adverse findings on serial cranial ultrasound (CUS) and near-term brain MRI (ntMRI), and Bayley-III scores in extremely preterm (EPT) toddlers. STUDY

designCohort analysis of Neonatal Research Network SUPPORT NEURO data. Associations between brain abnormalities, hand function, and Bayley-III scores were examined using chi-square and generalized linear mixed effect model analyses.

resultsA total of 433 children were included. Sixteen percent had hand function deficits; these were associated with late CUS (p < 0.001) abnormalities, white matter abnormality (WMA) on ntMRI (p < 0.001), and Bayley-III scores. Six percent had CP. Fourteen percent of children without and 50% of those with CP had hand function abnormalities.

conclusionsLate CUS findings and severity of WMA were significantly associated with hand function deficits. Hand function deficits were nearly three times more common than CP and may be a useful marker of early brain insult and predictor of preterm birth effects on development.

Indexed as

EchoencephalographyMagnetic Resonance ImagingBrainCohort StudiesDevelopmental DisabilitiesFemaleHandHumansInfantInfant, Extremely PrematureLinear ModelsMaleNeuropsychological Tests

Identifiers

PMID30692613
PMCPMC7092795

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.