Evidence map›Paper›PMID 30692588›Full record

ArticleJournal of exposure science & environmental epidemiology2020

Correlates of exposure to phenols, parabens, and triclocarban in the Study of Environment, Lifestyle and Fibroids.

Traci N Bethea, Amelia K Wesselink, Jennifer Weuve, Michael D McClean, Russ Hauser, Paige L Williams, Xiaoyun Ye, Antonia M Calafat, Donna D Baird, Lauren A Wise

Abstract read
In one paragraph

Article in Journal of exposure science & environmental epidemiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Traci N BetheaSlone Epidemiology Center at Boston University, Boston, MA, USA. tnb@bu.edu.
Amelia K WesselinkDepartment of Epidemiology, Boston University School of Public Health, Boston, MA, USA.
Jennifer WeuveDepartment of Epidemiology, Boston University School of Public Health, Boston, MA, USA.
Michael D McCleanDepartment of Environmental Health, Boston University School of Public Health, Boston, MA, USA.
Russ HauserDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Paige L WilliamsDepartment of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Xiaoyun YeNational Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Antonia M CalafatNational Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Donna D BairdEpidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA.
Lauren A WiseDepartment of Epidemiology, Boston University School of Public Health, Boston, MA, USA.

Funding

Uterine LeiomyomasZIAES049013 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI JUKIC, ANNE MARIE · 2009 to 2025
$14.7M
Endocrine disrupting chemicals and risk of uterine fibroids: a prospective studyR01ES024749 · NIEHS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI LAUREN A WISE · 2015 to 2026
$4.8M
ARRA NIH HHSNIEHS NIH HHS R01 ES024749
6 · The paper itself

Abstract

We performed a cross-sectional analysis to identify correlates of urinary concentrations of seven phenols (bisphenols A, F, and S; 2,4-dichlorophenol; 2,5-dichlorophenol; benzophenone-3; triclosan), triclocarban, and four parabens (butyl, ethyl, methyl, and propyl). We analyzed baseline data from 766 participants in the Study of Environment, Lifestyle, and Fibroids, a prospective cohort study of 1693 Black women aged 23-34 years residing in Detroit, Michigan (2010-2012). We collected data on demographic, behavioral, and anthropometric factors via telephone interviews, clinic visits, and self-administered questionnaires. For each biomarker, we used linear regression models to estimate mean differences in log-transformed, creatinine-corrected concentrations across factors of interest. Each biomarker was detected in >50% of participants. Median creatinine-corrected concentrations were the highest for methyl paraben (116.8 μg/g creatinine), propyl paraben (16.8 μg/g creatinine), and benzophenone-3 (13.4 μg/g creatinine). Variables most strongly associated with biomarker concentrations included season of urine collection, education, and body mass index (BMI). BMI was positively associated with bisphenol A and S and triclocarban concentrations and inversely associated with butyl and methyl paraben concentrations. In this cohort of Black women, exposure to phenols, parabens, and triclocarban was prevalent and several factors were associated with biomarker concentrations.

Indexed as

AdultBenzhydryl CompoundsBenzophenonesBiomarkersBisphenol A CompoundsCarbanilidesCohort StudiesCross-Sectional StudiesEnvironmental ExposureFemaleHumansLeiomyomaLife StyleMiddle AgedParabensPhenolsBenzhydryl CompoundsBenzophenonesBiomarkersbisphenol ABisphenol A CompoundsCarbanilidesmethylparabenoxybenzoneParabensPhenolspropylparabentriclocarbanTriclosanEndocrine disruptorsEpidemiologyPersonal exposurePopulation-based studies

Identifiers

PMID30692588
PMCPMC6661224

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.