ArticleInfection and immunity2019
Intracellular Degradation of Helicobacter pylori VacA Toxin as a Determinant of Gastric Epithelial Cell Viability.
Open access · bronzeAbstract read
In one paragraph
Article in Infection and immunity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.5field-weighted citation impact, top 8% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 29 citations in OpenAlex.
- Pathogenicity ofWorld journal of clinical oncology · 2025Review
- Update on the pathogenesis and clinical management ofWorld journal of gastrointestinal pathophysiology · 2025Review
- Application of Nanodrug Delivery Systems in Enhancing Treatment of Gastritis and Gastric Cancer: A Systematic Evaluation of Targeted Therapy.Pharmaceutics · 2025Review
- Taurine modulates host cell responses toInfection and immunity · 2024Article
- Structural Analysis of Membrane-associated Forms of Helicobacter pylori VacA Toxin.Journal of molecular biology · 2024Article
- Restoration of mitochondrial structure and function withinAdvances in microbiology · 2023Article
- The Relationship between Gastroduodenal Pathologies and Helicobacter pylori cagL (Cytotoxin-Associated Gene L) Polymorphism.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2023Article
- Mitochondrial Function in Health and Disease: Responses to Helicobacter pylori Metabolism and Impact in Gastric Cancer Development.Current topics in microbiology and immunology · 2023Article
- CRISPR/Cas9 Genome-Editing Technology and Potential Clinical Application in Gastric Cancer.Genes · 2022Review
- Helicobacter pylori Infection, Its Laboratory Diagnosis, and Antimicrobial Resistance: a Perspective of Clinical Relevance.Clinical microbiology reviews · 2022Review
- Electrochemical Immunosensor for Detection ofACS omega · 2022Article
- The crosstalk between bacteria and host autophagy: host defense or bacteria offense.Journal of microbiology (Seoul, Korea) · 2022Review
- Functional Properties of Oligomeric and Monomeric Forms of Helicobacter pylori VacA Toxin.Infection and immunity · 2021Article
- Gut Microbiome Alteration after Reboxetine Administration in Type-1 Diabetic Rats.Microorganisms · 2021Article
- Review
- Functional Properties of Helicobacter pylori VacA Toxin m1 and m2 Variants.Infection and immunity · 2020Article
- Review: Pathogenesis of Helicobacter pylori infection.Helicobacter · 2019Review
- AUF1-mediated inhibition of autophagic lysosomal degradation contributes to CagA stability andGut microbesArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 1 country.
Nora J FoegedingDepartment of Cell and Developmental Biology, Vanderbilt University, Nashville, Tennessee, USA.
Krishnan RaghunathanDepartment of Pediatrics, Children's Hospital of Pittsburgh, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Anne M CampbellDepartment of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Sun Wook KimDepartment of Cell and Developmental Biology, Vanderbilt University, Nashville, Tennessee, USA.
Ken S LauDepartment of Cell and Developmental Biology, Vanderbilt University, Nashville, Tennessee, USA.
Anne K KenworthyDepartment of Cell and Developmental Biology, Vanderbilt University, Nashville, Tennessee, USA.
Timothy L CoverDepartment of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA timothy.l.cover@vanderbilt.edu mohi@umich.edu.ORCID 0000-0001-8503-002X
Melanie D OhiLife Sciences Institute, University of Michigan, Ann Arbor, Michigan, USA timothy.l.cover@vanderbilt.edu mohi@umich.edu.
Vanderbilt University · USChildren's Hospital of Pittsburgh · USUniversity of Michigan · US
Funding
Understanding and Controlling p120 Dysfunction in CRCP50CA095103 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI COFFEY, ROBERT J. · 2002 to 2017
$33.6MTranslational Analysis CoreP30DK058404 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RICHARD M. PEEK · 2002 to 2026
$29.9MRole of Iron and B-Catenin Activation in Gastric CarcinogenesisP01CA116087 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RICHARD M. PEEK · 2009 to 2026
$27.5MStructure-function analysis of H. pylori VacAR01AI039657 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI TIMOTHY L COVER · 1996 to 2026
$8.3MMOLECULAR BIOPHYSICS TRAINING PROGRAM AT VANDERBILTT32GM008320 · NIGMS · VANDERBILT UNIVERSITY · PI CHAZIN, WALTER J. · 1989 to 2023
$7.9MType IV Protein Secretion in Helicobacter pyloriR01AI118932 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI COVER, TIMOTHY L, OHI, MELANIE DIANE · 2016 to 2025
$6.7MTuft cell heterogeneity in function, lineage, and structure in ileal inflammatory diseaseR01DK103831 · NIDDK · VANDERBILT UNIVERSITY · PI LAU, KEN S · 2016 to 2024
$4.4MFunction and assembly of toxin-stabilized domainsR01GM106720 · NIGMS · VANDERBILT UNIVERSITY · PI KENWORTHY, ANNE K · 2013 to 2020
$2.7MLSM880-Airyscan Confocal Microscope for Large Shared ResourceS10OD021630 · OD · VANDERBILT UNIVERSITY · PI WELLS, K. SAM · 2016 to 2016
$560kPathogenesis of Helicobacter pylori infectionI01BX000627 · VA · VETERANS HEALTH ADMINISTRATION · PI COVER, TIMOTHY L · 2011 to 2018
–BLRD VA I01 BX000627NCI NIH HHS P01 CA116087NCI NIH HHS P50 CA095103NIAID NIH HHS R01 AI039657NIAID NIH HHS R01 AI118932NIDDK NIH HHS P30 DK058404NIDDK NIH HHS R01 DK103831NIGMS NIH HHS R01 GM106720NIGMS NIH HHS T32 GM008320NIH HHS S10 OD021630
Abstract
PubMed holds no abstract for this paper.
Indexed as
AutophagyBacterial ProteinsCell LineCell SurvivalEpithelial CellsGastric MucosaHelicobacter InfectionsHelicobacter pyloriHumansHydrogen-Ion ConcentrationMuramidaseProtein StabilityProtein TransportProteolysisBacterial ProteinsMuramidaseVacA protein, Helicobacter pyloricell deathcell survivalHelicobacter pyloripore-forming toxinsVacA
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.