Evidence map›Paper›PMID 30692178›Full record

ArticleInfection and immunity2019

Identification of a Conserved, Orphan G Protein-Coupled Receptor Required for Efficient Pathogen Clearance in Caenorhabditis elegans.

Alexandra Anderson, Yee Lian Chew, William Schafer, Rachel McMullan

Open access · bronzeAbstract read
In one paragraph

Article in Infection and immunity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Innate immunity in C. elegans.Current topics in developmental biology · 2021
    Review
  7. Review
  8. Melatonin promotes sleep by activating the BK channel inProceedings of the National Academy of Sciences of the United States of America · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Alexandra AndersonDepartment of Life Sciences, Imperial College London, London, United Kingdom.
Yee Lian ChewNeurobiology Division, MRC Laboratory of Molecular Biology, Cambridge, United Kingdom.
William SchaferNeurobiology Division, MRC Laboratory of Molecular Biology, Cambridge, United Kingdom.
Rachel McMullanSchool of Life, Health and Chemical Sciences, The Open University, Milton, Keynes, United Kingdom rachel.mcmullan@open.ac.uk.ORCID 0000-0003-2677-8016
MRC Laboratory of Molecular Biology · GBImperial College London · GBThe Open University · GB

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5M
Medical Research Council MC-A023-5PB91Medical Research Council MC_U105185857NIH HHS P40 OD010440Wellcome TrustWellcome Trust WT088409AIA
6 · The paper itself

Abstract

G protein-coupled receptors contribute to host defense across the animal kingdom, transducing many signals involved in both vertebrate and invertebrate immune responses. While it has become well established that the nematode worm

Indexed as

ActinobacteriaAnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsReceptors, G-Protein-CoupledCaenorhabditis elegans ProteinsReceptors, G-Protein-CoupledCaenorhabditis elegansG protein-coupled receptorMicrobacterium nematophilumpathogen clearance

Identifiers

PMID30692178
PMCPMC6434109
OpenAlexW2913845466

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.