Evidence map›Paper›PMID 30692077›Full record

ArticleNan fang yi ke da xue xue bao = Journal of Southern Medical University2019

[Characteristics of BK polymavirus infection in kidney transplant recipients].

Yi Zhou, Leiyu Yao, Zhe Yu, Naiqian Cui, Fangxiang Fu, Yuedian Ye, Wenfeng Deng, Jian Xu, Shaojie Fu, Ruming Liu and 2 more

Abstract read
In one paragraph

Article in Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Yi ZhouFirst Clinical Medical School, Southern Medical University, Guangzhou 510515, China.
Leiyu YaoDepartment of Organ Transplantation, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Zhe YuDepartment of Organ Transplantation, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Naiqian CuiFirst Clinical Medical School, Southern Medical University, Guangzhou 510515, China.
Fangxiang FuDepartment of Organ Transplantation, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Yuedian YeFirst Clinical Medical School, Southern Medical University, Guangzhou 510515, China.
Wenfeng DengDepartment of Organ Transplantation, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Jian XuDepartment of Organ Transplantation, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Shaojie FuDepartment of Organ Transplantation, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Ruming LiuDepartment of Organ Transplantation, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Lixin YuDepartment of Organ Transplantation, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Yun MiaoDepartment of Organ Transplantation, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Southern Medical University · CNNanfang Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo analyze the characteristics of BK polymavirus (BKV) infection and the optimal time window for intervention in kidney transplant recipients (KTRs).

methodsWe retrospectively analyzed the clinical data and treatment regimens in 226 KTRs in our center between January, 2013 and January, 2018. Among the recipients, 157 had a urine BKV load ≥1.0×10

resultsAmong the 157 KTRs, 60 (38.2%) recipients were positive for urine BKV, 66 (42.0%) had BKV viruria, and 31(19.7%) had BKV viremia. The incidence of positive urine occult blood was significantly higher in BKV-positive recipients than in the control group (

conclusionsPositive urine occult blood after transplantation may be associated with BKV infection reactivation in some of the KTRs. BKV infection is sensitive to changes of plasma concentration of immunosuppressive agents. Early intervention of BKV replication in KTRs with appropriate dose reduction for immunosuppression can help to control virus replication and stabilize the allograft function.

Indexed as

Kidney TransplantationTransplant RecipientsViral LoadBK VirusHumansPolyomavirus InfectionsRetrospective StudiesTumor Virus InfectionsVirus ReplicationBK polymavirusimmunosuppressioninterventionrenaltransplantationurine occult blood

Identifiers

PMID30692077
PMCPMC6765578
OpenAlexW3024786325

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.