Evidence map›Paper›PMID 30691984›Full record

ArticleVaccine2019

PNAG-specific equine IgG

Joana N Rocha, Lawrence J Dangott, Waithaka Mwangi, Robert C Alaniz, Angela I Bordin, Colette Cywes-Bentley, Sara D Lawhon, Suresh D Pillai, Jocelyne M Bray, Gerald B Pier and 1 more

Open access · greenAbstract read
In one paragraph

Article in Vaccine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 26 citations in OpenAlex.

  1. Nebulization of an mRNA-encoded monoclonal antibody for passive immunization of foals against Rhodococcus equi.Molecular therapy : the journal of the American Society of Gene Therapy · 2025
    Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Serum Antibody Activity against Poly-Microbiology spectrum · 2021
    Article
  7. Response ofRadiation physics and chemistry (Oxford, England : 1993) · 2021
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Joana N RochaCollege of Veterinary Medicine & Biomedical Sciences, Texas A&M University, 660 Raymond Stotzer Pkwy, College Station, TX 77843-4475, United States. Electronic address: jrocha@cvm.tamu.edu.
Lawrence J DangottProtein Chemistry Laboratory, Texas A&M University, 300 Olsen Blvd, College Station, TX 77843, United States. Electronic address: dangott@tamu.edu.
Waithaka MwangiDepartment of Diagnostic Medicine/Pathobiology, Kansas State University, 1800 Denison Ave, Manhattan, KS 66506, United States. Electronic address: wmwangi@vet.k-state.edu.
Robert C AlanizDepartment of Microbial Pathogenesis and Immunology, Texas A&M University Health and Science Center, 206 Olsen Blvd, College Station, TX 77845, United States. Electronic address: alaniz@medicine.tamhsc.edu.
Angela I BordinCollege of Veterinary Medicine & Biomedical Sciences, Texas A&M University, 660 Raymond Stotzer Pkwy, College Station, TX 77843-4475, United States. Electronic address: abordin@cvm.tamu.edu.
Colette Cywes-BentleyHarvard Medical School, Brigham & Women's Hospital, 181 Longwood Ave, Boston, MA 02115, United States. Electronic address: ccywes@rics.bwh.harvard.edu.
Sara D LawhonCollege of Veterinary Medicine & Biomedical Sciences, Texas A&M University, 660 Raymond Stotzer Pkwy, College Station, TX 77843-4475, United States. Electronic address: slawhon@cvm.tamu.edu.
Suresh D PillaiNational Center for Electron Beam Research-IAEA Collaborative Centre for Electron Beam Technology, Texas A&M University, 400 Discovery Dr, College Station, TX 77845, United States. Electronic address: s-pillai@tamu.edu.
Jocelyne M BrayCollege of Veterinary Medicine & Biomedical Sciences, Texas A&M University, 660 Raymond Stotzer Pkwy, College Station, TX 77843-4475, United States.
Gerald B PierHarvard Medical School, Brigham & Women's Hospital, 181 Longwood Ave, Boston, MA 02115, United States. Electronic address: gpier@bwh.harvard.edu.
Noah D CohenCollege of Veterinary Medicine & Biomedical Sciences, Texas A&M University, 660 Raymond Stotzer Pkwy, College Station, TX 77843-4475, United States. Electronic address: ncohen@cvm.tamu.edu.
Texas A&M University · USBrigham and Women's Hospital · USKansas State University · USTexas A&M Health Science Center · US

Funding

Virulence and Immunity to StaphylcocciR01AI046706 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI PIER, GERALD B · 2001 to 2010
$4.1M
NIAID NIH HHS R01 AI046706
6 · The paper itself

Abstract

Prescottella equi (formerly Rhodococcus equi) is a facultative intracellular bacterial pathogen that causes severe pneumonia in foals 1-6 months of age, whereas adult horses are highly resistant to infection. We have shown that vaccinating pregnant mares against the conserved surface polysaccharide capsule, β-1 → 6-linked poly-N-acetyl glucosamine (PNAG), elicits opsonic killing antibody that transfers via colostrum to foals and protects them against experimental infection with virulent. R. equi. We hypothesized that equine IgG

Indexed as

PhagocytosisAcetylglucosamineActinomycetales InfectionsAge FactorsAnimalsAnimals, NewbornAntibodies, BacterialComplement C1Horse DiseasesHorsesImmunoglobulin GOpsonin ProteinsPneumonia, BacterialRhodococcus equiAcetylglucosamineAntibodies, BacterialComplement C1Immunoglobulin GOpsonin Proteinspoly-N-acetyl glucosamineComplementIgG(1)IgG(4/7)Intracellular bacteriaOpsonizationOpsonophagocytic killingRhodoccus equi

Identifiers

PMID30691984
PMCPMC8314964
OpenAlexW2911648210

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.