Evidence map›Paper›PMID 30691967›Full record

ArticleBiological psychiatry. Cognitive neuroscience and neuroimaging2019

Dynamic Causal Modeling of Insular, Striatal, and Prefrontal Cortex Activities During a Food-Specific Go/NoGo Task.

Qinghua He, Xiaolu Huang, Shuyue Zhang, Ofir Turel, Liangsuo Ma, Antoine Bechara

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biological psychiatry. Cognitive neuroscience and neuroimaging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  20. Cross-Hemispheric Complementary Prefrontal Mechanisms during Task Switching under Perceptual Uncertainty.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Qinghua HeFaculty of Psychology, Southwest University, Collaborative Innovation Center of Assessment toward Basic Education Quality, Beibei, Chongqing; Chongqing Collaborative Innovation Center for Brain Science, Collaborative Innovation Center of Assessment toward Basic Education Quality, Beibei, Chongqing; Southwest University Branch, Collaborative Innovation Center of Assessment toward Basic Education Quality, Beibei, Chongqing. Electronic address: heqinghua@swu.edu.cn.
Xiaolu HuangFaculty of Psychology, Southwest University, Collaborative Innovation Center of Assessment toward Basic Education Quality, Beibei, Chongqing.
Shuyue ZhangFaculty of Education, Guangxi Normal University, Guangxi Colleges and Universities Key Laboratory of Cognitive Neuroscience and Applied Psychology, Guilin, Guangxi, China.
Ofir TurelInformation Systems and Decision Sciences, California State University, Fullerton, California; Brain and Creativity Institute, University of Southern California, Los Angeles, California; Department of Psychology, University of Southern California, Los Angeles, California.
Liangsuo MaDepartment of Radiology, Virginia Commonwealth University, Richmond, Virginia; Institute for Drug and Alcohol Studies, Richmond, Virginia.
Antoine BecharaBrain and Creativity Institute, University of Southern California, Los Angeles, California; Department of Psychology, University of Southern California, Los Angeles, California.

Funding

Habitual & Neurocogonitive Processes in Adolescent Obesity PreventionU01HL097839 · NHLBI · CLAREMONT GRADUATE UNIVERSITY · PI REYNOLDS, KIM DANIEL · 2009 to 2014
$5.4M
Changes in Addictive Behaviors After Brain LesionsR01DA023051 · NIDA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI BECHARA, ANTOINE · 2008 to 2012
$2.4M
Neurocognitive Mechanisms of Decisions and Impulse Control in Nutrition BehaviorR01CA152062 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI AMES, SUSAN L., BECHARA, ANTOINE · 2011 to 2015
$1.9M
COGNITIVE AND NEURAL MECHANISMS OF SUBSTANCE ABUSER01DA011779 · NIDA · UNIVERSITY OF IOWA · PI BECHARA, ANTOINE · 1998 to 2004
$843k
NCI NIH HHS R01 CA152062NHLBI NIH HHS U01 HL097839NIDA NIH HHS R01 DA011779NIDA NIH HHS R01 DA023051
6 · The paper itself

Abstract

backgroundThis study aimed to investigate the dynamic interactions among three neural systems that are implicated in substance and behavioral addictions in response to food cues in young adults. These include an impulsive system involving the striatum, a reflective system involving the prefrontal cortex, and a homeostasis sensing system involving the insular cortex.

methodsCollege students (N = 45) with various levels of body mass index were recruited. Functional magnetic resonance imaging data were acquired while participants performed food-related Go/NoGo tasks, with low-calorie and high-calorie food cues. Participants were scanned under both food satiety and deprivation conditions. Dynamic causal modeling was applied to the data to examine the causal architecture of coupled or distributed dynamics among the aforementioned systems.

resultsParticipants showed difficulty inhibiting responses to high-calorie foods as suggested by higher false alarm rate and decision bias for low-calorie food Go task. This difficulty was enhanced during the food deprivation condition. Deprivation increased neural activity of both the insula and the striatum bilaterally in response to high-calorie foods during Go trials and anterior cingulate cortex and dorsolateral prefrontal cortex activity during NoGo trials. Dynamic causal modeling analysis revealed that food deprivation modulated the communications between the insula, striatum, and dorsolateral prefrontal cortex, and the modulations were positively associated with body mass index.

conclusionsThe results support tripartite views of decision making. Deprivation states, such as hunger, trigger insular activity, which modulates the balance between impulsive and reflective systems when facing tempting food cues.

Indexed as

FoodInhibition, PsychologicalAdolescentAdultCorpus StriatumCuesExecutive FunctionFemaleGyrus CinguliHumansHungerMagnetic Resonance ImagingMaleModels, TheoreticalPrefrontal CortexSatiationDeprivationDorsolateral prefrontal cortexDynamic causal modelingfMRIFoodInsulaStriatum

Identifiers

PMID30691967
PMCPMC6609512

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.