Evidence map›Paper›PMID 30691724›Full record

ArticleDiagnostic microbiology and infectious disease2019

Microbiology of combat-related extremity wounds: Trauma Infectious Disease Outcomes Study.

Katrin Mende, Laveta Stewart, Faraz Shaikh, William Bradley, Dan Lu, Margot R Krauss, Lauren Greenberg, Qilu Yu, Dana M Blyth, Timothy J Whitman and 2 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Diagnostic microbiology and infectious disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 41 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 2 countries.

Katrin MendeInfectious Disease Clinical Research Program, Preventive Medicine & Biostatistics Department, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Rd, Bethesda, MD, 20814, USA; Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., 6720A Rockledge Dr, Bethesda, MD, 20817, USA; Brooke Army Medical Center, 3551 Roger Brooke Dr, MCHE-MDI, JBSA Fort Sam Houston, TX 78234, USA. Electronic address: katrin.mende.ctr@mail.mil.
Laveta StewartInfectious Disease Clinical Research Program, Preventive Medicine & Biostatistics Department, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Rd, Bethesda, MD, 20814, USA; Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., 6720A Rockledge Dr, Bethesda, MD, 20817, USA.
Faraz ShaikhInfectious Disease Clinical Research Program, Preventive Medicine & Biostatistics Department, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Rd, Bethesda, MD, 20814, USA; Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., 6720A Rockledge Dr, Bethesda, MD, 20817, USA.
William BradleyInfectious Disease Clinical Research Program, Preventive Medicine & Biostatistics Department, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Rd, Bethesda, MD, 20814, USA; Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., 6720A Rockledge Dr, Bethesda, MD, 20817, USA; Brooke Army Medical Center, 3551 Roger Brooke Dr, MCHE-MDI, JBSA Fort Sam Houston, TX 78234, USA.
Dan LuInfectious Disease Clinical Research Program, Preventive Medicine & Biostatistics Department, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Rd, Bethesda, MD, 20814, USA; Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., 6720A Rockledge Dr, Bethesda, MD, 20817, USA.
Margot R KraussWestat, 1600 Research Blvd, Rockville, MD, 20850, USA.
Lauren GreenbergWestat, 1600 Research Blvd, Rockville, MD, 20850, USA.
Qilu YuWestat, 1600 Research Blvd, Rockville, MD, 20850, USA.
Dana M BlythBrooke Army Medical Center, 3551 Roger Brooke Dr, MCHE-MDI, JBSA Fort Sam Houston, TX 78234, USA.
Timothy J WhitmanWalter Reed National Military Medical Center, 8901 Rockville Pike, Bethesda, MD, 20889, USA.
Joseph L PetfieldLandstuhl Regional Medical Center, Landstuhl, Germany, CMR 402, APO, AE, 09180.
David R TribbleInfectious Disease Clinical Research Program, Preventive Medicine & Biostatistics Department, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Rd, Bethesda, MD, 20814, USA.
Uniformed Services University of the Health Sciences · USWestat (United States) · USHenry M. Jackson Foundation · USLandstuhl Regional Medical Center · DESan Antonio Military Medical Center · USWalter Reed National Military Medical Center · US

Funding

DATA CENTER FOR EPIDEMIOLOGIC INVESTIGATIONS OF HIVN01AI005072 · NIAID · NEW ENGLAND RESEARCH INSTITUTES, INC. · PI MCKINLAY, SONJA M · 1990 to 1994
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NIAID NIH HHS Y01 AI005072
6 · The paper itself

Abstract

We present extremity wound microbiology data from 250 combat casualties (2009-2012). Confirmed extremity wound infections (EWIs) were based on clinical and laboratory findings. Suspected EWIs had isolation of organisms from wound cultures with associated signs/symptoms not meeting clinical diagnostic criteria. Colonized wounds had organisms isolated without any infection suspicion. A total of 335 confirmed EWIs (131 monomicrobial and 204 polymicrobial) were assessed. Gram-negative bacteria were predominant (57% and 86% of monomicrobial and polymicrobial infections, respectively). In polymicrobial infections, 61% grew only bacteria, while 30% isolated bacteria and mold. Multidrug resistance was observed in 32% of isolates from first monomicrobial EWIs ±3 days of diagnosis, while it was 44% of isolates from polymicrobial EWIs. Approximately 96% and 52% of the suspected and colonized wounds, respectively, shared ≥1 organism in common with the confirmed EWI on the same patient. Understanding of combat-related EWIs can lead to improvements in combat casualty care.

Indexed as

Military PersonnelAnti-Infective AgentsBacteriaBacterial InfectionsCoinfectionDrug Resistance, MicrobialFungiHumansMycosesTreatment OutcomeUnited StatesWound InfectionAnti-Infective AgentsExtremity infectionsExtremity woundsOpen fracturesTrauma-related infectionsWound microbiology

Identifiers

PMID30691724
PMCPMC6520157
OpenAlexW2906740262

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.