Evidence map›Paper›PMID 30691504›Full record

ArticleHealth research policy and systems2019

New indicators and indexes for benchmarking university-industry-government innovation in medical and life science clusters: results from the European FP7 Regions of Knowledge HealthTIES project.

Laurel D Edmunds, Silvia Gluderer, Pavel V Ovseiko, Roel Kamerling, Jacqueline Ton, Laura Vis, Mario Jenni, Gregory Tutton, Helen Lawton-Smith, Márta Völgyiné Nadabán and 12 more

Abstract read
In one paragraph

Article in Health research policy and systems, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Laurel D EdmundsSir William Dunn School, University of Oxford, Oxford, United Kingdom.
Silvia GludererAstellas Pharma, Zürich, Switzerland.
Pavel V OvseikoSir William Dunn School, University of Oxford, Oxford, United Kingdom.
Roel KamerlingMedical Delta, Delft University of Technology, Delft, The Netherlands.
Jacqueline TonLeiden University Medical Center, Leiden, The Netherlands.
Laura VisProvince of South Holland, The Hague, The Netherlands.
Mario JenniBio-Technopark Schlieren-Zürich, Zurich,, Switzerland.
Gregory TuttonCloverton Holdings, Basel, Switzerland.
Helen Lawton-SmithDepartment of Management, Birkbeck, University of London, London, United Kingdom.
Márta Völgyiné NadabánIndependent Consultant, Debrecen, Hungary.
Máté RabInnonic Group, Debrecen, Hungary.
Jon ReesJon Rees Associates Ltd, Oxford, United Kingdom.
John AnsonOxford Gene Technology, Oxford, United Kingdom.
Alexander D RushforthNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, United Kingdom.
Maxine AllenBusiness Development Team, Medical Sciences Division, University of Oxford, Oxford, United Kingdom.
Alastair M BuchanSir William Dunn School, University of Oxford, Oxford, United Kingdom.
Montserrat VendrellBioCat, Bioregion of Catalonia, Barcelona, Spain.
Alex CastaBusiness Development Team, Medical Sciences Division, University of Oxford, Oxford, United Kingdom.
Gábor MehesFaculty of Public Health, University of Debrecen, Debrecen, Hungary.
Pancras C W HogendoornLeiden University Medical Center, Leiden, The Netherlands.
Ernst HafenInstitute of Molecular Systems Biology, ETH Zürich, Zurich, Switzerland.
A Bassim HassanSir William Dunn School, University of Oxford, Oxford, United Kingdom. bass.hassan@path.ox.ac.uk.

Funding

European Institute of Innovation and Technology EIT Health-Rare Cancer KIC Stage 1Health Services Research Programme Oxford Biomedical Research CentreSeventh Framework Programme 265550
6 · The paper itself

Abstract

backgroundWhile the European Union is striving to become the 'Innovation Union', there remains a lack of quantifiable indicators to compare and benchmark regional innovation clusters. To address this issue, a HealthTIES (Healthcare, Technology and Innovation for Economic Success) consortium was funded by the European Union's Regions of Knowledge initiative, research and innovation funding programme FP7. HealthTIES examined whether the health technology innovation cycle was functioning differently in five European regional innovation clusters and proposed regional and joint actions to improve their performance. The clusters included BioCat (Barcelona, Catalonia, Spain), Medical Delta (Leiden, Rotterdam and Delft, South Holland, Netherlands), Oxford and Thames Valley (United Kingdom), Life Science Zürich (Switzerland), and Innova Észak-Alföld (Debrecen, Hungary).

methodsAppreciation of the 'triple helix' of university-industry-government innovation provided the impetus for the development of two quantifiable innovation indexes and related indicators. The HealthTIES H-index is calculated for disease and technology platforms based on the h-index proposed by Hirsch. The HealthTIES Innovation Index is calculated for regions based on 32 relevant quantitative and discriminative indicators grouped into 12 categories and 3 innovation phases, namely 'Input' (n = 12), 'Innovation System' (n = 9) and 'Output' (n = 11).

resultsThe HealthTIES regions had developed relatively similar disease and technology platform profiles, yet with distinctive strengths and weaknesses. The regional profiles of the innovation cycle in each of the three phases were surprisingly divergent. Comparative assessments based on the indicators and indexes helped identify and share best practice and inform regional and joint action plans to strengthen the competitiveness of the HealthTIES regions.

conclusionThe HealthTIES indicators and indexes provide useful practical tools for the measurement and benchmarking of university-industry-government innovation in European medical and life science clusters. They are validated internally within the HealthTIES consortium and appear to have a degree of external prima facie validity. Potentially, the tools and accompanying analyses can be used beyond the HealthTIES consortium to inform other regional governments, researchers and, possibly, large companies searching for their next location, analyse and benchmark 'triple helix' dynamics within their own networks over time, and to develop integrated public-private and cross-regional research and innovation strategies in Europe and beyond.

Indexed as

BenchmarkingBiological Science DisciplinesBiomedical ResearchGovernmentIndustryUniversitiesBiomedical TechnologyDelivery of Health CareEuropeEuropean UnionHumansKnowledgeTechnologybiotechnologyEuropean Unioninnovation indexlife sciencesmedical sciencespublic policyRegional innovation clusterRegions of Knowledgetriple helixuniversity–industry–government innovation

Identifiers

PMID30691504
PMCPMC6350323

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.