Trial reportBMC public health2019
Effectiveness of community adolescent treatment supporters (CATS) interventions in improving linkage and retention in care, adherence to ART and psychosocial well-being: a randomised trial among adolescents living with HIV in rural Zimbabwe.
Trial report in BMC public health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 96 papers, 11 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
96 citing papers in PubMed, 11 syntheses or guidelines pooled it, 144 citations in OpenAlex.
- Implementation components and delivery structures of adolescent peer navigation as a workforce model: a scoping review.BMC global and public health · 2026Pooled it
- Antiretroviral Therapy Adherence Interventions in the Era of Universal Test and Treat: A Hybrid Systematic-Narrative Literature Review of Global Evidence.AIDS and behavior · 2026Pooled it
- Community-based interventions against HIV-related stigma: a systematic review of evidence in Sub-Saharan Africa.Systematic reviews · 2025Pooled it
- What works in 21st century skills education in sub-Saharan Africa: a systematic review.Frontiers in psychology · 2025Pooled it
- Primary-level and community worker interventions for the prevention of mental disorders and the promotion of well-being in low- and middle-income countries.The Cochrane database of systematic reviews · 2023Pooled it
- Pooled it
- Systematic review: Development of a person-centered care framework within the context of HIV treatment settings in sub-Saharan Africa.Tropical medicine & international health : TM & IH · 2022Pooled it
- Psychosocial interventions for improving engagement in care and health and behavioural outcomes for adolescents and young people living with HIV: a systematic review and meta-analysis.Journal of the International AIDS Society · 2021Pooled it
- Interventions to Improve Adherence to Antiretroviral Therapy (ART) in Sub-Saharan Africa: An Updated Systematic Review.International journal of environmental research and public health · 2021Pooled it
- Impacts of social support on the treatment outcomes of drug-resistant tuberculosis: a systematic review and meta-analysis.BMJ open · 2020Pooled it
- Interventions to Improve Antiretroviral Therapy Adherence Among Adolescents and Youth in Low- and Middle-Income Countries: A Systematic Review 2015-2019.AIDS and behavior · 2020Pooled it
- Trial
- Trial
- The transient effect of a peer support intervention to improve adherence among adolescents and young adults failing antiretroviral therapy in Harare, Zimbabwe: a randomized control trial.AIDS research and therapy · 2021Trial
- A group-based mental health intervention for young people living with HIV in Tanzania: results of a pilot individually randomized group treatment trial.BMC public health · 2020Trial
- Determinants of retention into HIV care among adolescents living with HIV in two selected districts in Copperbelt Province of Zambia.Journal of public health research · 2026Article
- Challenges with drug management of children and adolescents living with human immunodeficiency virus on antiretroviral therapy: A narrative review.African journal of primary health care & family medicine · 2026Review
- Clinical outcomes after the implementation of a patient-centered care program applied to newly admitted people with HIV in Mexico City: a retrospective cohort study.AIDS research and therapy · 2026Article
- Peer Group Support to Children and Adolescents with HIV: A Randomized Controlled Trial in Vietnam.AIDS and behavior · 2026Article
- A comparative analysis of social support, risk behaviors, and HIV health service use among adolescent and young males and females in Lusaka, Zambia.Global epidemiology · 2026Article
36 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
backgroundEngagement with community adolescent treatment supporters (CATS) improves adherence, psychosocial well-being, linkage and retention in care among adolescents living with HIV. However, there is an urgent need for empirical evidence of the effectiveness of this approach, in order to inform further programmatic development, national and international policy, guidelines and service delivery for adolescents living with HIV. This study set out to determine the effectiveness of CATS services on improving linkage to services and retention in care, adherence and psychosocial well-being among adolescents living with HIV in Zimbabwe.
methodsA randomised trial was conducted in Gokwe South district, Zimbabwe over a period of 12 months. Ninety-four HIV-positive adolescents, 10-15 years old, on antiretroviral therapy were recruited to the study. 47 participants received standard of care from the Ministry of Health and Child Care and 47 received the same standard of care plus CATS services. Data collection involved a questionnaire which was administered at baseline then repeated at three, six, nine and twelve months for all participants. Survey questions on confidence, self-esteem and self-worth had a three-point Likert scale. Stigma, quality of life and the linkages to services and retention questions had a five-point Likert scale.
resultsSurvey questionnaires were completed with response rates of 40 out of 47 (85%) for the intervention arm, and 28 out of 47 (60%) for the control arm, at end-line. The intervention group were 3.9 times more likely to adhere to treatment compared to the control group. Linkage to services and retention in care within the intervention group increased compared with a decrease in the control arm. The intervention group reported a statistically significant increase in confidence, self-esteem, self-worth (p < 0.001) and quality of life compared (p = 0.028) with a decrease in the control arm.
conclusionsThis study found that adolescents receiving the CATS service had improved linkage to services and retention in care, improved adherence and improved psychosocial well-being compared to adolescents who did not have access to such services.
trial registrationPACTR201711002755428 . Registered 11 November 2017. Retrospectively registered.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.