ArticleBMC geriatrics2019
Frailty, transition in frailty status and all-cause mortality in older adults of a Taichung community-based population.
Article in BMC geriatrics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 3 of them syntheses that pooled it.
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Who cites it
35 citing papers in PubMed, 3 syntheses or guidelines pooled it, 107 citations in OpenAlex.
- Association of frailty and mortality risk in community-dwelling older adults: a systematic review and meta-analysis of 59 international prospective cohort studies.BMC public health · 2026Pooled it
- Frailty and risks of all-cause and cause-specific death in community-dwelling adults: a systematic review and meta-analysis.BMC geriatrics · 2022Pooled it
- Global Incidence of Frailty and Prefrailty Among Community-Dwelling Older Adults: A Systematic Review and Meta-analysis.JAMA network open · 2019Pooled it
- Changes in frailty, intensive blood pressure treatment, and risks of adverse clinical outcomes: a post hoc analysis of the SPRINT trial.BMC medicine · 2025Trial
- Dynamic frailty trajectories and risk of age-related macular degeneration: a prospective cohort study in UK Biobank.GeroScience · 2026Article
- Care and Health Needs of Older Patients with Frailty in General Practice.Healthcare (Basel, Switzerland) · 2026Article
- Relationship of depression and mortality in community-residing elderly individuals: mediating role of frailty and quality of life.BMC geriatrics · 2025Article
- Impact of social vulnerability on frailty transition among older adults in China: a national two-year cohort study.Journal of global health · 2025Article
- Frailty and Cognitive Decline in Hospitalized Elderly Patients: Associations with Clinical and Laboratory Parameters.Medical science monitor : international medical journal of experimental and clinical research · 2025Article
- Cognitive Frailty and Its Risk Factors Among Patients With Chronic Kidney Disease Receiving Hemodialysis: A Cross-Sectional Study.Nursing & health sciences · 2025Article
- Prevalence and impact of frailty on unplanned hospitalizations among adult patients with cancer in Taiwan.The oncologist · 2025Article
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- Association of changes in frailty with mortality in the aged with hypertension.Scientific reports · 2025Article
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- Associations Between Frailty and the Increased Risk of Adverse Outcomes Among 38,950 UK Biobank Participants With Prediabetes: Prospective Cohort Study.JMIR public health and surveillance · 2023Article
- Urinary Phthalate Metabolites and Slow Walking Speed in the Korean Elderly Environmental Panel II Study.Environmental health perspectives · 2023Article
- Geriatric symptoms associated with healthy life expectancy in older people in Japan.Environmental health and preventive medicine · 2023Article
- Factors Determining the Occurrence of Frailty Syndrome in Hospitalized Older Patients.International journal of environmental research and public health · 2022Article
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Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPrevious studies have reported the associations of frailty phenotype or its components with mortality. However, studies that explored the effects of transition in frailty status on mortality were far less in Asian or Chinese. The aim of this study was to evaluate baseline frailty status and one-year change of frailty status in relation to all-cause mortality in Taiwanese community-dwelling older adults who participated in the Taichung Community Health Study for Elders.
methodsWe conducted a community-based prospective cohort study. A total of 921 community-dwelling elderly men and women aged 65-99 years in Taichung City were enrolled in 2009-2010 and were followed up through 2016. We adopted the definition of frailty proposed by Fried et al., including five components: shrinking, weakness, poor endurance and energy, slowness, and low physical activity. Cox proportional hazards models were used to determine adjusted hazard ratios (HRs) of mortality with 95% confidence intervals (CIs) for frailty at baseline and one-year change in frailty status.
resultsThere were 160 deaths during the follow-up period. The mortality rates in groups of robust and frail were 20.26 and 84.66 per 1000 person-years respectively. After multivariate adjustment, the HR (CIs) for baseline frailty was 2.67 (1.73-4.12). Poor endurance and energy [1.88 (1.03-3.42)], slowness [2.60 (1.76-3.83)] and weakness [1.65 (1.16-2.33)] were found to be predictors of mortality. Increased risks in mortality for subgroups of robust-to-frail [2.76 (1.22-6.27)], frail-to-robust [3.87 (1.63, 9.19)], and frail-to-frail [4.08 (1.92-8.66)] over one-year period were observed compared with those remaining robust.
conclusionBaseline frailty status and one-year change in frailty status are associated with 6-year all-cause mortality among Taiwanese elderly adults. Frailty may be useful for identifying older adults at high risks for mortality prevention.
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