Evidence map›Paper›PMID 30691236›Full record

ArticleMolecules (Basel, Switzerland)2019

Serum Metabolomics Identifies Altered Bioenergetics, Signaling Cascades in Parallel with Exposome Markers in Crohn's Disease.

Yunjia Lai, Jingchuan Xue, Chih-Wei Liu, Bei Gao, Liang Chi, Pengcheng Tu, Kun Lu, Hongyu Ru

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 1 pooled it
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 1 synthesis or guideline pooled it, 76 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Host-pathobiont interactions in Crohn's disease.Nature reviews. Gastroenterology & hepatology · 2025
    Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Cardiovascular manifestations of inflammatory bowel diseases and the underlying pathogenic mechanisms.American journal of physiology. Regulatory, integrative and comparative physiology · 2023
    Review
  19. Effects of Exogenous Ergothioneine onInternational journal of molecular sciences · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Yunjia LaiDepartment of Environmental Sciences and Engineering, Gillings School of Global Public Health, CB #7431, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. lai7@live.unc.edu.
Jingchuan XueDepartment of Environmental Sciences and Engineering, Gillings School of Global Public Health, CB #7431, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. xuejc@email.unc.edu.
Chih-Wei LiuDepartment of Environmental Sciences and Engineering, Gillings School of Global Public Health, CB #7431, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. ericleah@email.unc.edu.
Bei GaoNIH West Coast Metabolomics Center, University of California at Davis, Davis, CA 95616, USA. beigao@ucdavis.edu.
Liang ChiDepartment of Environmental Sciences and Engineering, Gillings School of Global Public Health, CB #7431, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. liang16@live.unc.edu.
Pengcheng TuDepartment of Environmental Sciences and Engineering, Gillings School of Global Public Health, CB #7431, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. ptu@live.unc.edu.
Kun LuDepartment of Environmental Sciences and Engineering, Gillings School of Global Public Health, CB #7431, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. kunlu@unc.edu.
Hongyu RuDepartment of Population Health and Pathobiology, North Carolina State University, Raleigh, NC 27695, USA. hru@ncsu.edu.
University of North Carolina at Chapel Hill · USNorth Carolina State University · USUniversity of California, Davis · US

Funding

UNC-CH CENTER FOR ENVIRONMENTAL HEALTH &SUSCEPTIBILITYP30ES010126 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Stephanie Engel · 2001 to 2026
$36.3M
Translational Research Support CoreP30ES025128 · NIEHS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI Sue Fenton · 2015 to 2026
$18.3M
NIEHS NIH HHS P30 ES010126NIEHS NIH HHS P30ES025128, R01ES024950, P30ES010126
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Energy MetabolismMetabolomeMetabolomicsSignal TransductionAmino AcidsBiomarkersCrohn DiseaseFatty AcidsHumansLipid MetabolismOxidation-ReductionAmino AcidsBiomarkersFatty AcidsCrohn’s DiseaseDocosahexaenoic acidErgothioneineExposomeGut MicrobiotaInflammatory Bowel DiseaseSerum MetabolomicsTryptophan Metabolism

Identifiers

PMID30691236
PMCPMC6385106
OpenAlexW2912249416

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.