Evidence map›Paper›PMID 30691228›Full record

ArticleInternational journal of molecular sciences2019

Development of a Dual-Vector System Utilizing MicroRNA Mimics of the

Krisztina Koczka, Wolfgang Ernst, Dieter Palmberger, Miriam Klausberger, Lisa Nika, Reingard Grabherr

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Krisztina KoczkaAustrian Centre of Industrial Biotechnology - acib, A-1190 Vienna, Austria. krisztina.koczka@boku.ac.at.
Wolfgang ErnstAustrian Centre of Industrial Biotechnology - acib, A-1190 Vienna, Austria. wolfgang.ernst@boku.ac.at.
Dieter PalmbergerAustrian Centre of Industrial Biotechnology - acib, A-1190 Vienna, Austria. dieter.palmberger@boku.ac.at.
Miriam KlausbergerAustrian Centre of Industrial Biotechnology - acib, A-1190 Vienna, Austria. miriam.klausberger@boku.ac.at.
Lisa NikaDepartment of Biotechnology, University of Natural Resources and Life Sciences, A-1190 Vienna, Austria. lisa.nika@boku.ac.at.
Reingard GrabherrAustrian Centre of Industrial Biotechnology - acib, A-1190 Vienna, Austria. reingard.grabherr@boku.ac.at.ORCID 0000-0002-4501-927X

Funding

Austrian Science Fund FWF W 1224Federal Ministry of Science, Research and Economy (BMWFW), the Federal Ministry of Traffic, Innovation and Technology (bmvit), the Styrian Business Promotion Agency SFG, the Standortagentur Tirol, the Government of Lower Austria and Business Agency Vienna COMET-Funding Program managed by the Austrian Research Promotion Agency FFGPhD programme "BioTop - Biomolecular Technology of Proteins" Austrian Science Funds, Project number FWF W1224
6 · The paper itself

Abstract

The baculovirus-insect cell expression system is a popular tool for the manufacturing of various attractive recombinant products. Over the years, several attempts have been made to engineer and further improve this production platform by targeting host or baculoviral genes by RNA interference. In this study, an inducible knockdown system was established in insect (

Indexed as

AnimalsBacterial ProteinsBacteriophage T7BaculoviridaeDNA-Directed RNA PolymerasesGene Knockdown TechniquesGenetic EngineeringLepidopteraLuminescent ProteinsMicroRNAsPromoter Regions, GeneticRecombinant ProteinsSf9 CellsViral ProteinsBacterial Proteinsbacteriophage T7 RNA polymeraseDNA-Directed RNA PolymerasesLuminescent ProteinsMicroRNAsRecombinant ProteinsViral Proteinsyellow fluorescent protein, Bacteriaartificial miRNAbaculovirus-insect cell expression systemRNA interference

Identifiers

PMID30691228
PMCPMC6387257

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.