ArticleNutrients2019
Metabolomic Salivary Signature of Pediatric Obesity Related Liver Disease and Metabolic Syndrome.
Article in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.
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Who cites it
26 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- A Systematic Review on Metabolomics Analysis in Hearing Impairment: Is It a Possible Tool in Understanding Auditory Pathologies?International journal of molecular sciences · 2023Pooled it
- Paediatric obesity: a systematic review and pathway mapping of metabolic alterations underlying early disease processes.Molecular medicine (Cambridge, Mass.) · 2021Pooled it
- Metabolic features in plasma and urine of obese children and their association with MAFLD risk.Frontiers in nutrition · 2026Article
- A repository of the salivary metabolome and its key drivers in 1436 European children.EBioMedicine · 2025Article
- Advancements and Challenges in Salivary Metabolomics for Early Detection and Monitoring of Systemic Diseases.MedComm · 2025Review
- Pediatric metabolic (dysfunction)-associated fatty liver disease: current insights and future perspectives.Hepatology international · 2024Review
- Critical Factors in Sample Collection and Preparation for Clinical Metabolomics of Underexplored Biological Specimens.Metabolites · 2024Review
- Distinct gut flora profile induced by postnatal trans-fat diet in gestationally bisphenol A-exposed rats.PloS one · 2024Article
- Salivary Metabolomic Signatures and Body Mass Index in Italian Adolescents: A Pilot Study.Journal of the Endocrine Society · 2023Article
- Extending the breadth of saliva metabolome fingerprinting by smart template strategies and effective pattern realignment on comprehensive two-dimensional gas chromatographic data.Analytical and bioanalytical chemistry · 2023Article
- Metabolome × Microbiome Changes Associated with a Diet-Induced Reduction in Hepatic Fat among Adolescent Boys.Metabolites · 2023Article
- Review
- Metabolomics prospect of obesity and metabolic syndrome; a systematic review.Journal of diabetes and metabolic disorders · 2022Review
- Contribution of Metabolomics to the Understanding of NAFLD and NASH Syndromes: A Systematic Review.Metabolites · 2021Review
- Serum metabolomics in chickens infected with Cryptosporidium baileyi.Parasites & vectors · 2021Article
- Salivary Biomarkers and Oral Health in Liver Transplant Recipients, with an Emphasis on Diabetes.Diagnostics (Basel, Switzerland) · 2021Article
- Untargeted metabolomics as a diagnostic tool in NAFLD: discrimination of steatosis, steatohepatitis and cirrhosis.Metabolomics : Official journal of the Metabolomic Society · 2021Article
- Exploring extra dimensions to capture saliva metabolite fingerprints from metabolically healthy and unhealthy obese patients by comprehensive two-dimensional gas chromatography featuring Tandem Ionization mass spectrometry.Analytical and bioanalytical chemistry · 2021Article
- Metabolic Syndrome: Past, Present and Future.Nutrients · 2020Article
- Minimally Invasive Biospecimen Collection for Exposome Research in Children's Health.Current environmental health reports · 2020Review
Corrections and comments
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Authors and funding
13 authors.
Funding
Abstract
Pediatric obesity-related metabolic syndrome (MetS) and nonalcoholic fatty liver disease (NAFLD) are increasingly frequent conditions with a still-elusive diagnosis and low-efficacy treatment and monitoring options. In this study, we investigated the salivary metabolomic signature, which has been uncharacterized to date. In this pilot-nested case-control study over a transversal design, 41 subjects (23 obese patients and 18 normal weight (NW) healthy controls), characterized based on medical history, clinical, anthropometric, and laboratory data, were recruited. Liver involvement, defined according to ultrasonographic liver brightness, allowed for the allocation of the patients into four groups: obese with hepatic steatosis ([St+],
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