Evidence map›Paper›PMID 30691106›Full record

ArticleInternational journal of molecular sciences2019

Autophagy Activation by

Seok Jeong Yoon, Chae Jin Lim, Hwa-Jee Chung, Joo-Hwan Kim, Yang Hoon Huh, Keedon Park, Sekyoo Jeong

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Natural Modulators of Key Signaling Pathways in Skin Inflammageing.Clinical, cosmetic and investigational dermatology · 2024
    Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. (+)-BornylInternational journal of molecular sciences · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Seok Jeong YoonR&D Center, Incospharm Corp, 328 Techno-2-ro, Yuseong-gu, Daejeon 34036, Korea. sjyoon@incospharm.com.
Chae Jin LimR&D Center, Incospharm Corp, 328 Techno-2-ro, Yuseong-gu, Daejeon 34036, Korea. cjlim@incospharm.com.
Hwa-Jee ChungR&D Center, Incospharm Corp, 328 Techno-2-ro, Yuseong-gu, Daejeon 34036, Korea. hjchung@incospharm.com.
Joo-Hwan KimDepartment of Life Science, Gachon University, 1342 Seongnamdaero, Sujeong-gu, Seongnam, Gyeonggi-do 13120, Korea. kimjh2009@gachon.ac.kr.
Yang Hoon HuhElectron Microscopy Research Center, Korea Basic Science Institute, 162 Yeongudanji-ro, Ochang-eup, Cheongwon-gu, Cheongju, Chungbuk 28119, Korea. hyh1127@kbsi.re.kr.
Keedon ParkR&D Center, Incospharm Corp, 328 Techno-2-ro, Yuseong-gu, Daejeon 34036, Korea. kdpark@incospharm.com.
Sekyoo JeongR&D Center, Incospharm Corp, 328 Techno-2-ro, Yuseong-gu, Daejeon 34036, Korea. sekyoo.jeong@incospharm.com.ORCID 0000-0002-9201-0227
Komipharm International (South Korea) · KRGachon University · KRKorea Basic Science Institute · KRSeowon University · KR

Funding

Korea Basic Science Institute Korea Basic Science Institute grant C38916Ministry of Health and Welfare Korean Health Technology R&D Project. Grant No. HN15C0105
6 · The paper itself

Abstract

Pollution-induced skin damage results in oxidative stress; cellular toxicity; inflammation; and, ultimately, premature skin aging. Previous studies suggest that the activation of autophagy can protect oxidation-induced cellular damage and aging-like changes in skin. In order to develop new anti-pollution ingredients, this study screened various kinds of natural extracts to measure their autophagy activation efficacy in cultured dermal fibroblast. The stimulation of autophagy flux by the selected extracts was further confirmed both by the expression of proteins associated with the autophagy signals and by electron microscope.

Indexed as

AMP-Activated Protein KinasesAsteraceaeAutophagyBenzopyrenesCadmium ChlorideCells, CulturedCytokinesEnvironmental PollutantsEpidermal CellsFibroblastsGene Expression RegulationHumansMicroscopy, Electron, TransmissionOxidative StressPhosphorylationPlant ExtractsAMP-Activated Protein KinasesBenzopyrenesCadmium ChlorideCytokinesEnvironmental PollutantsPlant ExtractsTOR Serine-Threonine Kinasesanti-inflammationanti-pollutionautophagyCrepidiastrum denticulatum extractskin barrier

Identifiers

PMID30691106
PMCPMC6386979
OpenAlexW2913834595

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.