Evidence map›Paper›PMID 30691022›Full record

ReviewJournal of clinical medicine2019

Coupling between Osseointegration and Mechanotransduction to Maintain Foreign Body Equilibrium in the Long-Term: A Comprehensive Overview.

Luis Amengual-Peñafiel, Manuel Brañes-Aroca, Francisco Marchesani-Carrasco, María Costanza Jara-Sepúlveda, Leopoldo Parada-Pozas, Ricardo Cartes-Velásquez

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Implications of considering peri-implant bone loss a disease, a narrative review.Clinical implant dentistry and related research · 2022
    Review
  9. Review
  10. Review
  11. Article
  12. Are Oral Implants the Same As Teeth?Journal of clinical medicine · 2019
    Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Luis Amengual-PeñafielDental Implantology Unit, Hospital Leonardo Guzmán, Antofagasta 1240835, Chile. luisamengualp@gmail.com.
Manuel Brañes-ArocaFaculty of Sciences, Universidad de Chile, Santiago 7800003, Chile. branesmd.1@vtr.net.
Francisco Marchesani-CarrascoClínica Marchesani, Concepción 4070566, Chile. francisco@marchesani.cl.
María Costanza Jara-SepúlvedaClínica Marchesani, Concepción 4070566, Chile. mconstanzajara@gmail.com.
Leopoldo Parada-PozasRegenerative Medicine Center, Hospital Clínico de Viña del Mar, Viña del Mar 2520626, Chile. dr.polo@ejerciciosalud.cl.
Ricardo Cartes-VelásquezSchool of Dentistry, Universidad Andres Bello, Concepción 4300866, Chile. cartesvelasquez@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The permanent interaction between bone tissue and the immune system shows us the complex biology of the tissue in which we insert oral implants. At the same time, new knowledge in relation to the interaction of materials and the host, reveals to us the true nature of osseointegration. So, to achieve clinical success or perhaps most importantly, to understand why we sometimes fail, the study of oral implantology should consider the following advice equally important: a correct clinical protocol, the study of the immunomodulatory capacity of the device and the osteoimmunobiology of the host. Although osseointegration may seem adequate from the clinical point of view, a deeper vision shows us that a Foreign Body Equilibrium could be susceptible to environmental conditions. This is why maintaining this cellular balance should become our therapeutic target and, more specifically, the understanding of the main cell involved, the macrophage. The advent of new information, the development of new implant surfaces and the introduction of new therapeutic proposals such as therapeutic mechanotransduction, will allow us to maintain a healthy host-implant relationship long-term.

Indexed as

immunomodulationmarginal bone lossmechanotransductionoral implantsosseointegration

Identifiers

PMID30691022
PMCPMC6407014

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.