Evidence map›Paper›PMID 30690903›Full record

ReviewMaternal & child nutrition2019

Measuring growth and medium- and longer-term outcomes in malnourished children.

Victor O Owino, Alexia J Murphy-Alford, Marko Kerac, Paluku Bahwere, Henrik Friis, James A Berkley, Alan A Jackson

Open access · bronzeAbstract readReview
In one paragraph

Review in Maternal & child nutrition, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 47 citations in OpenAlex.

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  18. Pediatric undernutrition defined by body composition-are we there yet?The American journal of clinical nutrition · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 6 countries.

Victor O OwinoNutritional and Health Related Environmental Studies Section, Division of Health, International Atomic Energy Agency, Vienna, Austria.ORCID 0000-0003-4493-0501
Alexia J Murphy-AlfordNutritional and Health Related Environmental Studies Section, Division of Health, International Atomic Energy Agency, Vienna, Austria.
Marko KeracDepartment of Population Health, London School of Hygiene and Tropical Medicine, London, UK.
Paluku BahwereValid International, Oxford, UK.
Henrik FriisDepartment of Nutrition, Exercise and Sports, University of Copenhagen, Frederiksberg, Denmark.
James A BerkleyDirector, The Childhood Acute Illness & Nutrition (CHAIN) Network, Nairobi, Kenya.
Alan A JacksonHuman Nutrition, International Malnutrition Task Force, Southampton General Hospital, Southampton, UK.
International Atomic Energy Agency · ATAngkor Hospital for Children · KHLondon School of Hygiene & Tropical Medicine · GBSouthampton General Hospital · GBStatistics Belgium · BEUniversity of Copenhagen · DK

Funding

Medical Research Council MR/M007367/1
6 · The paper itself

Abstract

Severe and moderate acute malnutrition are among the leading causes of mortality among children in low- and middle-income countries. There is strong evidence that growth assessed anthropometrically from conception to 2 years of age marks later risk of ill health. This is central to the concept of the developmental origins of adult disease and is presumed to be related to modification of developmental processes during critical "window(s)" of vulnerability. Interventions to treat acute malnutrition have resulted in dramatic increase in the number of affected children surviving. Ensuring that these children thrive to fulfil their full physical and cognitive potential is a new challenge. Integral to this challenge is the need to be able to measure how earlier insults relate to the ability to survive and thrive to productive adulthood. Despite its obvious value, routine anthropometry does not adequately indicate how earlier adverse exposures affect more refined aspects of growth. Anthropometry is inadequate for predicting how disruption of healthy growth might modulate risk of disease or any subsequent interventions that correct this risk. A clear characterisation of healthy child growth is needed for determining which component best predicts later outcomes. The extent to which postnatal acute malnutrition is a consequence of maternal factors acting preconception or in utero and their relationship to postnatal health and long-term risk of non-communicable diseases is not clear. Body-composition measurement has significant untapped potential allowing us to translate and better understand the relationship between early insults and interventions on early growth in the short-term and long-term health outcomes.

Indexed as

Body CompositionChild DevelopmentAnthropometryChild Nutritional Physiological PhenomenaChild Nutrition DisordersChild, PreschoolDeveloping CountriesFetal Nutrition DisordersHumansInfantInfant Nutritional Physiological PhenomenaSevere Acute Malnutritionacute malnutritionassessment of nutritional statusbody compositionchronic diseaseDoHaDgrowth

Identifiers

PMID30690903
PMCPMC7199054
OpenAlexW2914128685

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.