Evidence map›Paper›PMID 30690554›Full record

ArticleSocial cognitive and affective neuroscience2019

Different modulation effects of Tai Chi Chuan and Baduanjin on resting-state functional connectivity of the default mode network in older adults.

Jiao Liu, Jing Tao, Weilin Liu, Jia Huang, Xiehua Xue, Ming Li, Mingge Yang, Jingfang Zhu, Courtney Lang, Joel Park and 4 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Social cognitive and affective neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 9 pooled it
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 9 syntheses or guidelines pooled it, 77 citations in OpenAlex.

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  10. A Randomized Controlled Trial of Tai Chi Chih or Health Education for Geriatric Depression.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2022
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  20. The Science of Tai Chi andJournal of integrative and complementary medicine · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 2 countries.

Jiao LiuFujian Rehabilitation Tech Co-innovation Center, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, China.
Jing TaoFujian Key Laboratory of Rehabilitation Technology, Fuzhou, Fujian, China.
Weilin LiuFujian Key Laboratory of Rehabilitation Technology, Fuzhou, Fujian, China.
Jia HuangFujian Key Laboratory of Rehabilitation Technology, Fuzhou, Fujian, China.
Xiehua XueAffiliated Rehabilitation Hospital, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, China.
Ming LiAffiliated Rehabilitation Hospital, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, China.
Mingge YangCollege of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, China.
Jingfang ZhuCollege of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, China.
Courtney LangDepartment of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA, USA.
Joel ParkDepartment of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA, USA.
Yiheng TuDepartment of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA, USA.
Georgia WilsonDepartment of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA, USA.
Lidian ChenFujian Key Laboratory of Rehabilitation Technology, Fuzhou, Fujian, China.
Jian KongDepartment of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA, USA.
Fujian University of Traditional Chinese Medicine · CNHarvard University · USMassachusetts General Hospital · US

Funding

The Neurobiology of Placebo and Nocebo Effects: A Brain Imaging StudyR01AT006364 · NCCIH · MASSACHUSETTS GENERAL HOSPITAL · PI KONG, JIAN · 2011 to 2015
$3.6M
NCCIH NIH HHS R01 AT006364
6 · The paper itself

Abstract

The default mode network (DMN) plays an important role in age-related cognitive decline. This study aims to explore the modulation effect of two mind-body interventions (Tai Chi Chuan and Baduanjin) on DMN in elderly individuals. Participants between 50 and 70 years old were recruited and randomized into a Tai Chi Chuan, Baduanjin or control group. The Wechsler Memory Scale-Chinese Revision and resting-state fMRI scans were administered at baseline and following 12 weeks of exercise. Seed-based resting-state functional connectivity (rsFC) was calculated. We found that (i) compared to the Baduanjin group, Tai Chi Chuan was significantly associated with increased rsFC between the medial prefrontal cortex (mPFC) and right putamen/caudate and (ii) compared to the control group, Tai Chi Chuan increased posterior cingulate cortex rsFC with the right putamen/caudate, while Baduanjin decreased rsFC between the mPFC and orbital prefrontal gyrus/putamen. Baseline mPFC rsFC with orbital prefrontal gyrus was negatively correlated with visual reproduction subscore. These results suggest that both Tai Chi Chuan and Baduanjin can modulate the DMN, but through different pathways. Elucidating the mechanisms underlying different mind-body interventions may shed light on the development of new methods to prevent age-related diseases as well as other disorders associated with disrupted DMN.

Indexed as

AgedBrain MappingFemaleGyrus CinguliHumansMagnetic Resonance ImagingMaleMiddle AgedNeural PathwaysPrefrontal CortexRandom AllocationRestTai JiagingBaduanjindefault mode networkmemorymind–body exerciseresting-state functional connectivityTai Chi Chuan

Identifiers

PMID30690554
PMCPMC6374601
OpenAlexW2913403919

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.