ArticleThe journal of pain2019
Development of the Revised Opioid Risk Tool to Predict Opioid Use Disorder in Patients with Chronic Nonmalignant Pain.
Article in The journal of pain, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
47 citing papers in PubMed, 1 synthesis or guideline pooled it, 116 citations in OpenAlex.
- Elective surgery in ankle and foot disorders-best practices for management of pain: a guideline for clinicians.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2022Guideline
- Can Patient-centered Education and Pain Management Delivered by Coaches Improve Pain Outcomes After Orthopaedic Trauma? A Randomized Trial.Clinical orthopaedics and related research · 2024Trial
- Clinical Instruments Assessing Harms and Benefits of Long-Term Opioid Therapy for Chronic Pain: A Scoping Review.Journal of general internal medicine · 2026Article
- Opioid Risk Tool Scores are Not Associated With Opioid Misuse After Elective General Surgery: A Prospective Study.The Journal of surgical research · 2026Observational
- Substance use monitoring in supportive oncology: surveillance is not a clinical outcome, and policing is not a therapeutic framework.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Responsible AI for safer opioid risk management in older adults.npj health systems · 2026Article
- Developing and Validating a Machine Learning Algorithm to Predict the Risk of Incident Opioid Use Disorder Among OneFlorida+ Patients: Prognostic Modeling Study.Journal of medical Internet research · 2026Article
- Prediction of opioid use disorder among patients with chronic non-cancer pain receiving long-term opioid therapy.Pain medicine (Malden, Mass.) · 2026Article
- Latent Classes of Adverse Childhood Experiences (ACEs) and Adult Substance-use Problems and Psychosocial Outcomes: Complex and Heterogeneous Associations.International journal of mental health and addiction · 2026Article
- Psychiatric, Cardiovascular and Skeletal Risks of Codeine versus Oxycodone in Hip Osteoarthritis: A Population-Based Cohort Study.Drug design, development and therapy · 2026Article
- Comparative effectiveness of opioid versus opioid-free analgesia after outpatient breast surgery: PAIN-Alt trial protocol.BMJ open · 2025Article
- Article
- Women With Gynecologic Cancers: Screening for Substance Use Disorders Is Key.Journal of the advanced practitioner in oncology · 2025Article
- Travelling the Last Mile - Bringing Evidence to Individuals in Israel : a commentary on building capacity in implementation science.Israel journal of health policy research · 2025Article
- Opioid-use disorder and reported pain after spine surgery: Risk-group patterns in cognitive-appraisal processes in a longitudinal cohort study.North American Spine Society journal · 2025Article
- Disruptions in Reward-Guided Decision-Making Functions Are Predictive of Greater Oral Oxycodone Self-Administration in Male and Female Rats.Biological psychiatry global open science · 2025Article
- Consensus statement on chronic pain treatment in cancer survivors.Journal of anesthesia · 2025Review
- The American Society of Pain and Neuroscience (ASPN) Guidelines for Advanced Practice Providers in Interventional Spine and Pain Management Practice.Journal of pain research · 2025Article
- Risk Stratification for Postoperative Opioid Induced Respiratory Depression: A Retrospective Case-Control Analysis of Existing Validated Tools.Journal of pain research · 2025Article
- Opioid Risk Tool, in-hospital opioid exposure, and opioid demand predict pain outcomes following traumatic injury.Journal of health psychology · 2024Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
The Opioid Risk Tool (ORT) is a commonly used measure of risk of aberrant drug-related behaviors in patients with chronic pain prescribed opioid therapy. In this study, the discriminant predictive validity of the ORT was evaluated in a unique cohort of patients with chronic nonmalignant pain (CNMP) on long-term opioid therapy who displayed no evidence of developing an opioid use disorder (OUD) and a sample of patients with CNMP who developed an OUD after commencing opioid therapy. Results revealed that the original ORT was able to discriminate between patients with and without OUDs (odds ratio = 1.624; 95% confidence interval [CI] = 1.539-1.715, P < .001). A weighted ORT eliminating the gender-specific history of preadolescent sexual abuse item revealed comparable results (odds ratio = 1.648, 95% CI = 1.539-1.742, P < .001). A revised unweighted ORT removing the history of preadolescent sexual abuse item was notably superior in predicting the development of OUD in patients with CNMP on long-term opioid therapy (odds ratio = 3.085; 95% CI = 2.725-3.493; P < .001) with high specificity (.851; 95% CI = .811-.885), sensitivity (.854; 95% CI = .799-.898), positive predictive value (.757; 95% CI = .709-.799), and negative predictive value (.914; 95% CI = .885-.937). Perspective: The revised ORT is the first tool developed on a unique cohort to predict the risk of developing an OUD in patients with CNMP receiving opioid therapy, as opposed to aberrant drug-related behaviors that can reflect a number of other issues. The revised ORT has clinical usefulness in providing clinicians a simple, validated method to rapidly screen for the risk of developing OUD in patients on or being considered for opioid therapy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.