Evidence map›Paper›PMID 30690001›Full record

ArticleEuropean journal of pharmacology2019

Calcium/calmodulin regulates signaling at the α

Briana Gebert-Oberle, Jennifer Giles, Sarah Clayton, Quang-Kim Tran

Open access · greenAbstract read
In one paragraph

Article in European journal of pharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Briana Gebert-OberleDepartment of Physiology and Pharmacology, Des Moines University Osteopathic Medical Center, Ryan Hall 258, 3200 Grand Avenue, Des Moines, IA 50312, United States.
Jennifer GilesDepartment of Physiology and Pharmacology, Des Moines University Osteopathic Medical Center, Ryan Hall 258, 3200 Grand Avenue, Des Moines, IA 50312, United States.
Sarah ClaytonDepartment of Physiology and Pharmacology, Des Moines University Osteopathic Medical Center, Ryan Hall 258, 3200 Grand Avenue, Des Moines, IA 50312, United States.
Quang-Kim TranDepartment of Physiology and Pharmacology, Des Moines University Osteopathic Medical Center, Ryan Hall 258, 3200 Grand Avenue, Des Moines, IA 50312, United States. Electronic address: kim.tran@dmu.edu.
Des Moines University Osteopathic Medical Center · US

Funding

Regulation of GPER-mediated Signaling in the Vasculature by CalmodulinR15HL112184 · NHLBI · DES MOINES UNIV OSTEOPATHIC MEDICAL CTR · PI TRAN, KIM · 2012 to 2012
$362k
NHLBI NIH HHS R15 HL112184
6 · The paper itself

Abstract

Cardiovascular functions are mediated by multiple 7-pass transmembrane receptors whose activation promotes contraction or relaxation of the tissues. The α

Indexed as

Amino Acid SequenceCalciumCalmodulinDose-Response Relationship, DrugHEK293 CellsHumansProtein BindingReceptors, Adrenergic, alpha-1Signal TransductionCalciumCalmodulinReceptors, Adrenergic, alpha-1CalciumCalmodulinPhosphorylationSubmembrane domainα(1A) adrenoceptor

Identifiers

PMID30690001
PMCPMC6409194
OpenAlexW2914351738

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.