ArticlePLoS computational biology2019
A low-threshold potassium current enhances sparseness and reliability in a model of avian auditory cortex.
Article in PLoS computational biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed.
- Nonlinear effects of intrinsic dynamics on temporal encoding in a model of avian auditory cortex.PLoS computational biology · 2021Article
- Experience- and Sex-Dependent Intrinsic Plasticity in the Zebra Finch Auditory Cortex during Song Memorization.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Article
- Invariant neural responses for sensory categories revealed by the time-varying information for communication calls.PLoS computational biology · 2019Article
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2 authors.
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Abstract
Birdsong is a complex vocal communication signal, and like humans, birds need to discriminate between similar sequences of sound with different meanings. The caudal mesopallium (CM) is a cortical-level auditory area implicated in song discrimination. CM neurons respond sparsely to conspecific song and are tolerant of production variability. Intracellular recordings in CM have identified a diversity of intrinsic membrane dynamics, which could contribute to the emergence of these higher-order functional properties. We investigated this hypothesis using a novel linear-dynamical cascade model that incorporated detailed biophysical dynamics to simulate auditory responses to birdsong. Neuron models that included a low-threshold potassium current present in a subset of CM neurons showed increased selectivity and coding efficiency relative to models without this current. These results demonstrate the impact of intrinsic dynamics on sensory coding and the importance of including the biophysical characteristics of neural populations in simulation studies.
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