Evidence map›Paper›PMID 30689098›Full record

Trial reportSleep & breathing = Schlaf & Atmung2019

Adherence to CPAP with a nasal mask combined with mandibular advancement device versus an oronasal mask: a randomized crossover trial.

Antoine Léotard, Matthieu Lesgoirres, Najeh Daabek, Marius Lebret, Sebastien Bailly, Alain Verain, Fréderic Series, Jean-Louis Pépin, Jean-Christian Borel

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Sleep & breathing = Schlaf & Atmung, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01889472 (Impact of Nasal Mask/Oronasal Mask on Compliance to Treatment With Continuous Positive Airway Pressure), which is not on this map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01889472 naterminatednot on this map

Impact of Nasal Mask/Oronasal Mask on Compliance to Treatment With Continuous Positive Airway Pressure (CPAP) in Patients With Obstructive Sleep Apnea

TypeinterventionalSponsorLaval UniversityRan2013 to 2017Enrolled15ConditionsObstructive Sleep ApneaArmsNasal mask and oral appliance vs oro-nasal mask during autoCPAP therapy
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Maximizing outcomes by multimodal treatment in obstructive sleep apnea: a systematic review and meta-analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Antoine LéotardHP2, INSERM U1042, University Grenoble Alpes, F-38000, Grenoble, France.
Matthieu LesgoirresAGIR à dom. Association, 36 bd du Vieux Chêne, F-38240, Meylan, France.
Najeh DaabekHP2, INSERM U1042, University Grenoble Alpes, F-38000, Grenoble, France.
Marius LebretHP2, INSERM U1042, University Grenoble Alpes, F-38000, Grenoble, France. mariuslebret@gmail.com.ORCID http://orcid.org/0000-0001-8414-3110
Sebastien BaillyHP2, INSERM U1042, University Grenoble Alpes, F-38000, Grenoble, France.
Alain VerainSleep and Exercise Laboratory, Thorax-Vaisseaux Department, Grenoble-Alpes University Hospital, Saint-Martin-d'Hères, France.
Fréderic SeriesCentre de recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Québec (IUCPQ) Université Laval, Québec, QC, G1V4G5, Canada.
Jean-Louis PépinHP2, INSERM U1042, University Grenoble Alpes, F-38000, Grenoble, France.
Jean-Christian BorelHP2, INSERM U1042, University Grenoble Alpes, F-38000, Grenoble, France.
Inserm · FRAGIR à dom · FRInstitut universitaire de cardiologie et de pneumologie de Québec · CAUniversité Grenoble Alpes · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeEvidence for the management of CPAP-treated obstructive sleep apnea suggests that oronasal masks reduce mouth leaks at the expense of higher pressures and poorer adherence. Some authors have proposed the use of mandibular advancement devices in combination with nasal masks to address this. The aim of this study was to assess adherence to CPAP after 1 month's use of a nasal mask with a mandibular advancement device and to compare adherence with an oronasal mask.

methodsA randomized crossover trial design to assess whether a mandibular advancement device combined with a nasal mask would improve CPAP adherence compared to an oronasal mask.

resultsThere was no improvement in CPAP adherence and self-reported interface-related pain was significantly higher with the combined treatment.

conclusionsAlthough the combined treatment reduced pressures, likely by improving upper airway patency, it may only be appropriate for a small number of patients due to associated discomfort.

trial registrationNCT01889472.

Indexed as

MasksPatient ComplianceAdultContinuous Positive Airway PressureCross-Over StudiesEquipment and SuppliesFemaleHumansMaleMandibular AdvancementMiddle AgedNoseSleep Apnea, ObstructiveContinuous positive airway pressureMandibular advancement deviceNasal maskObstructive sleep apneaTreatment adherence and compliance

Identifiers

PMID30689098
OpenAlexW2912150170

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.