ArticleEuropean radiology2019
Changes in quantitative parameters of pulmonary nonsolid nodule induced by lung inflation according to paired inspiratory and expiratory computed tomography imaging.
Article in European radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed, 2 citations in OpenAlex.
- Moran's I-driven habitat radiomics: A biologically plausible and temporally robust approach for risk stratification of lung adenocarcinoma invasiveness.European journal of radiology open · 2026Article
- Effect of respiratory phase on three-dimensional quantitative parameters of pulmonary subsolid nodules in low-dose computed tomography screening for lung cancer.Journal of thoracic disease · 2025Article
- A wavelet features derived radiomics nomogram for prediction of malignant and benign early-stage lung nodules.Scientific reports · 2021Article
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveTo evaluate quantitative parameters of nonsolid nodules on paired inspiratory and expiratory computed tomography (CT) and to examine whether these parameters are sensitive to lung inflation reflected by lung volume.
methodsThirty-three patients with 41 nonsolid nodules were included in this prospective study. Paired inspiratory and low-dose respiratory plain chest CT were performed. The volume and density of nonsolid nodule(s), both lungs, the right and left lung, and five lobes, were analyzed in inspiratory and expiratory CT scans. The ratio of expiratory to inspiratory parameters was calculated and labeled as parameter
resultsNonsolid nodule volumes on expiratory CT were reduced by 19.8% ± 12.9%, while the density was increased by 11.4% ± 8.8%. The volume of nonsolid nodules was significantly greater on inspiratory compared with expiratory CT (p < 0.001). The density of nonsolid nodules was significantly greater on expiratory than inspiratory CT (p < 0.001). The volume
conclusionVolume changes in nonsolid nodules were more sensitive than density changes in expiratory phase. The density of lower lobe nodules was more susceptible to respiration. Expiratory scanning is not recommended for quantification of nonsolid nodules and/or follow-up. KEY POINTS: • The nonsolid nodule volume on expiratory CT was reduced by 19.8% ± 12.9%. • The nonsolid nodule density on expiratory CT was increased by 11.4% ± 8.8%. • The volume
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