Evidence map›Paper›PMID 30688651›Full record

ArticleeLife2019

Molecular basis of synaptic specificity by immunoglobulin superfamily receptors in

Shouqiang Cheng, James Ashley, Justyna D Kurleto, Meike Lobb-Rabe, Yeonhee Jenny Park, Robert A Carrillo, Engin Özkan

Open access · goldAbstract read
In one paragraph

Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 48 citations in OpenAlex.

  1. Article
  2. Article
  3. FETCH enables fluorescent labeling of membrane proteins in vivo with spatiotemporal control inProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  4. Review
  5. Article
  6. Molecular and Cellular Mechanisms of Motor Circuit Development.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Review
  7. Article
  8. Article
  9. Article
  10. bioRxiv : the preprint server for biology · 2023
    Article
  11. Structure and evolution of neuronal wiring receptors and ligands.Developmental dynamics : an official publication of the American Association of Anatomists · 2023
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Establishment and Maintenance of Neural Circuit Architecture.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Shouqiang ChengDepartment of Biochemistry and Molecular Biology, University of Chicago, Chicago, United States.
James AshleyDepartment of Molecular Genetics and Cell Biology, University of Chicago, Chicago, United States.
Justyna D KurletoDepartment of Biochemistry and Molecular Biology, University of Chicago, Chicago, United States.
Meike Lobb-RabeDepartment of Molecular Genetics and Cell Biology, University of Chicago, Chicago, United States.
Yeonhee Jenny ParkDepartment of Biochemistry and Molecular Biology, University of Chicago, Chicago, United States.
Robert A CarrilloDepartment of Molecular Genetics and Cell Biology, University of Chicago, Chicago, United States.ORCID 0000-0002-2067-9861
Engin ÖzkanDepartment of Biochemistry and Molecular Biology, University of Chicago, Chicago, United States.ORCID 0000-0002-0263-6729
University of Chicago · USJagiellonian University · PL

Funding

User Training and OutreachP30GM124165 · NIGMS · CORNELL UNIVERSITY · PI Nozomi Ando, J Christopher Fromme · 2018 to 2026
$34.2M
X-ray Absorption Spectroscopy (XAS) pp.711-759P41GM103393 · NIGMS · STANFORD UNIVERSITY · PI HODGSON, KEITH O · 2012 to 2019
$30.6M
Molecular And Cellular Biology Training ProgramT32GM007183 · NIGMS · UNIVERSITY OF CHICAGO · PI GLICK, BENJAMIN S, RICE, PHOEBE A · 1985 to 2021
$23.9M
MOLECULAR GENETICS OF DROSOPHILA CNS DEVELOPMENTR01NS028182 · NINDS · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI Engin Ozkan, KAI G ZINN · 1990 to 2026
$7.3M
Pixel Array Detector for Macromolecular CrystallographyS10OD021527 · OD · CORNELL UNIVERSITY · PI EALICK, STEVEN E · 2016 to 2016
$2.0M
Molecular Recognition Principles, Engineering and Function of Neural Wiring ReceptorsR01NS097161 · NINDS · UNIVERSITY OF CHICAGO · PI OZKAN, ENGIN · 2016 to 2020
$1.8M
Interactions Between IgSF Proteins in Neural Circuit FormationK01NS102342 · NINDS · UNIVERSITY OF CHICAGO · PI CARRILLO, ROBERT ARNULFO · 2017 to 2019
$684k
NIGMS NIH HHS P30 GM124165NIGMS NIH HHS P41 GM103393NIGMS NIH HHS T32 GM007183NIH HHS S10 OD021527NINDS NIH HHS K01 NS102342NINDS NIH HHS R01 NS028182NINDS NIH HHS R01 NS097161
6 · The paper itself

Abstract

In stereotyped neuronal networks, synaptic connectivity is dictated by cell surface proteins, which assign unique identities to neurons, and physically mediate axon guidance and synapse targeting. We recently identified two groups of immunoglobulin superfamily proteins in

Indexed as

Amino Acid SequenceAnimalsConserved SequenceCrystallography, X-RayDrosophila melanogasterDrosophila ProteinsImmunoglobulinsPhylogenyProtein BindingProtein MultimerizationReceptors, Cell SurfaceStructural Homology, ProteinSynapsesDrosophila ProteinsImmunoglobulinsReceptors, Cell Surfacecell surface receptorscrystal structureD. melanogasterimmunoglobulin superfamilymolecular biophysicsneuromuscular systemneuroscienceprotein engineeringstructural biologysynapse specificity

Identifiers

PMID30688651
PMCPMC6374074
OpenAlexW2913280679

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.