ArticleExperimental and clinical psychopharmacology2019
Initial application of a human laboratory model for estimating the motivational substitutability of e-cigarettes for combustible cigarettes.
Article in Experimental and clinical psychopharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Modeling the effect of stress on vaping behavior among young adults: A randomized cross-over pilot study.Drug and alcohol dependence · 2021Trial
- Evaluating the substitutability of fruit versus menthol and tobacco-flavored e-cigarettes on combustible cigarette cessation: Randomized clinical trial protocol.Contemporary clinical trials communications · 2026Article
- Effects of short-term nicotine deprivation on delay discounting among young, experienced, exclusive ENDS users: An initial study.Experimental and clinical psychopharmacology · 2023Article
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Authors and funding
5 authors.
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Abstract
This pilot study tested a novel human laboratory model for estimating the extent to which electronic cigarettes (e-cigarettes) serve as motivational substitutes for combustible cigarettes. The model assesses 3 parameters of substitutability, including the: (a) increase in motivational reward value of e-cigarettes after tobacco deprivation; (b) reduction in the reward value of combustible cigarettes after e-cigarette administration; and (c) comparability of the withdrawal-suppressing effects of e-cigarettes versus combustible cigarettes. Dual users (daily smokers, vaped 4+ days/week, M age = 35.3) attended 4 visits after 16-h tobacco product abstinence. For 2 visits, participants completed withdrawal measures and a task assessing smoking's reward value preceded by either: satiation by vaping or sustained tobacco product deprivation. For 2 other visits, participants completed withdrawal measures and a task assessing vaping's reward value preceded by either: continued deprivation versus satiation by smoking. Tobacco product deprivation (vs. satiation by smoking) increased vaping's reward value, indicated by nonsignificantly greater likelihood of initiating vaping versus abstaining for money (d = -.26; adjusted p [padj] = .08) and more vaping episodes purchased (β = .22; padj = .08). Satiation by vaping (vs. deprivation) nonsignificantly reduced smoking initiation (d = .46; padj = .09) and significantly decreased number of cigarettes purchased (β = -.29; padj = .04). Relative to deprivation, vaping suppressed withdrawal-related negative affect, smoking and vape urge, and anhedonia (ds ≥ .54). The magnitude of vaping-induced and smoking-induced withdrawal suppression did not significantly differ for all outcomes other than smoking urge, which was more strongly reduced by smoking (d = -1.57) than vaping (d = -.64). Future application and extension of this model may advance tobacco regulatory science and policy addressing e-cigarette use among smokers. (PsycINFO Database Record (c) 2019 APA, all rights reserved).
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