Evidence map›Paper›PMID 30688494›Full record

ArticleNeuropsychology2019

Risk tolerance measured by probability discounting among individuals with primary mood and psychotic disorders.

Kamber L Hart, Hannah E Brown, Joshua L Roffman, Roy H Perlis

Abstract read
In one paragraph

Article in Neuropsychology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
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  11. Review
  12. Article
  13. Anhedonia and Suicide.Current topics in behavioral neurosciences · 2022
    Review
  14. A Behavioral Economic Model of Help-Seeking for Depression.Perspectives on behavior science · 2021
    Article
  15. Risky decision-making in major depressive disorder: A three-level meta-analysis.International journal of clinical and health psychology : IJCHP
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kamber L HartCenter for Quantitative Health, Massachusetts General Hospital.ORCID 0000-0002-0168-645X
Hannah E BrownCenter for Quantitative Health, Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School.
Joshua L RoffmanMassachusetts General Hospital and Harvard Medical School.
Roy H PerlisMassachusetts General Hospital and Harvard Medical School.

Funding

Research ProjectP50MH106933 · NIMH · HARVARD MEDICAL SCHOOL · PI KOHANE, ISAAC S. · 2014 to 2018
$17.0M
NHGRI NIH HHSNIMH NIH HHSNIMH NIH HHS P50 MH106933
6 · The paper itself

Abstract

objectiveChange in risk tolerance is a feature of multiple psychiatric disorders and may contribute to adverse outcomes. We used a probability discounting (PD) task to measure risk-taking behavior among individuals with bipolar disorder (BPAD), major depressive disorder (MDD), schizoaffective disorder (SCAD), and schizophrenia (SCZ).

methodA PD task was administered to 117 patients and 88 healthy controls (HCs), along with a cognitive battery using the Cambridge Neuropsychological Test Automated Battery, and relevant symptomatology scales. We examined differences in PD rates between diagnostic groups, and compared with HCs, while controlling for potential confounding factors including measures of cognitive functioning.

resultsIndividuals with a diagnosis of BPAD or SCAD/SCZ prefer smaller, more guaranteed rewards rather than larger, less likely rewards as compared with healthy controls (p = .002 and p = .034, respectively). There was no effect of performance on cognitive tasks, antipsychotic treatment, or symptomatology on the rate of probability discounting.

conclusionThis study supports the transdiagnostic measurement of risk-taking behaviors, even when such behaviors are not the primary area of psychopathology. Quantifying risk-taking may enable targeted therapeutic strategies across disorders. (PsycINFO Database Record (c) 2019 APA, all rights reserved).

Indexed as

Risk-TakingAdultBipolar DisorderCognitionFemaleHumansMajor Depressive DisorderMaleMiddle AgedNeuropsychological TestsPsychotic DisordersReward

Identifiers

PMID30688494
PMCPMC10034864

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.