Evidence map›Paper›PMID 30688082›Full record

Trial reportClinical pediatrics2019

Effect of Donor Milk Supplementation on Breastfeeding Outcomes in Term Newborns: A Randomized Controlled Trial.

Laura R Kair, Valerie J Flaherman, Tarah T Colaizy

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Clinical pediatrics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Balancing access to donor human milk: Rationing vs expanding use.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Supplementation-based hypoglycemia guidelines including donor breast milk reduce NICU admission.Journal of perinatology : official journal of the California Perinatal Association · 2021
    Article
  8. Article
  9. Article
  10. Article
  11. Disparities in Donor Human Milk Supplementation Among Well Newborns.Journal of human lactation : official journal of International Lactation Consultant Association · 2020
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Laura R Kair1 University of Iowa, Iowa City, IA, USA.ORCID 0000-0003-4311-6292
Valerie J Flaherman3 University of California, San Francisco, CA, USA.
Tarah T Colaizy1 University of Iowa, Iowa City, IA, USA.

Funding

UC Davis Clinical and Translational Science CenterUL1TR001860 · NCATS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI KENYON, NICHOLAS J., LYLES, COURTNEY REES · 2016 to 2025
$47.3M
The University of Iowa Clinical and Translational Science AwardUL1TR002537 · NCATS · UNIVERSITY OF IOWA · PI HANSEN, MARLAN R, WINOKUR, PATRICIA · 2018 to 2022
$20.0M
The University of Iowa Clinical and Translational Science AwardU54TR001356 · NCATS · UNIVERSITY OF IOWA · PI WINOKUR, PATRICIA · 2015 to 2016
$7.1M
NCATS NIH HHS U54 TR001356NCATS NIH HHS UL1 TR001860NCATS NIH HHS UL1 TR002537
6 · The paper itself

Abstract

backgroundPasteurized donor human milk (DHM) use for healthy newborns is increasing; however, no studies have explored its effect on breastfeeding outcomes. PATIENTS AND

methodsWe enrolled 60 healthy, term breastfeeding newborns with ≥4.5% weight loss in the first 36 hours in a randomized controlled trial. Thirty newborns were randomly assigned to early limited-volume DHM supplementation and 30 newborns to exclusive breastfeeding. Mothers were surveyed at 1 week and 1, 2, and 3 months regarding the mode of infant feeding. Comparing infants randomized to DHM supplementation with those exclusively breastfeeding, there was no significant difference in the proportion using formula at 1 week (21% vs 7%, P = .15), nor in the proportion of any breastfeeding (79% vs 90%, P = .30) or breastfeeding without formula at 3 months (62% vs 77%, P = .27). Conclusion For newborns with ≥4.5% weight loss in the first 36 hours, early limited-volume supplementation with DHM is unlikely to have a significant favorable impact on breastfeeding outcomes.

Indexed as

Infant FormulaMilk, HumanAdultBreast FeedingFemaleFollow-Up StudiesHumansInfant CareInfant, NewbornMaleOutcome Assessment, Health CareWeight Lossbreastfeedingbreast milkdonor human milkdonor milkmilk bankingneonate

Identifiers

PMID30688082
PMCPMC6456417

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.