ArticleDiabetes & metabolism journal2019
Impact of Cytomegalovirus Disease on New-Onset Type 2 Diabetes Mellitus: Population-Based Matched Case-Control Cohort Study.
Article in Diabetes & metabolism journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
19 citing papers in PubMed, 34 citations in OpenAlex.
- Plasma exosome proteomics in different glucose statuses: a cross-sectional study on type 2 diabetes pathogenesis.Clinical proteomics · 2026Article
- Acyclic graphs to define models of relationships between human cytomegalovirus, cardiovascular disease and all-cause mortality in UK Biobank.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025Article
- Review
- Health impact of a hypothetical intervention on immune burden of cytomegalovirus (CMV) among older adults in the US: a prospective analysis of the Health and Retirement Study Cohort.Lancet regional health. Americas · 2025Article
- Dysregulation of NK cell subsets and phenotypes in COVID-19 patients with comorbid type 2 diabetes.Clinical science (London, England : 1979) · 2025Article
- Molecular mechanisms of viral oncogenesis in haematological malignancies: perspectives from metabolic reprogramming, epigenetic regulation and immune microenvironment remodeling.Experimental hematology & oncology · 2025Review
- Is Pollution the Primary Driver of Infectious Syndemics?Pathogens (Basel, Switzerland) · 2024Review
- An analysis of risk factors for spontaneously occurring type 2 diabetes mellitus in rhesus macaques (Macaca mulatta).Journal of medical primatology · 2024Article
- Connecting the Dots: How Herpes Viruses Influence Type 2 Diabetes: Insights from Experimental Researches.Clinical medicine insights. Endocrinology and diabetes · 2024Article
- The effects of cytomegalovirus on brain structure following sport-related concussion.Brain : a journal of neurology · 2023Article
- Does COVID-19 Infection Increase the Risk of Diabetes? Current Evidence.Current diabetes reports · 2023Review
- Infections and immunity: associations with obesity and related metabolic disorders.Journal of pathology and translational medicine · 2023Review
- Health impact of seven herpesviruses on (pre)diabetes incidence and HbADiabetologia · 2022Article
- The Role of CMV Infection in Primary Lesions, Development and Clinical Expression of Atherosclerosis.Journal of clinical medicine · 2022Review
- Human MicroRNAs Attenuate the Expression of Immediate Early Proteins and HCMV Replication during Lytic and Latent Infection in Connection with Enhancement of Phosphorylated RelA/p65 (Serine 536) That Binds to MIEP.International journal of molecular sciences · 2022Article
- Review
- Type 2 diabetes and viral infection; cause and effect of disease.Diabetes research and clinical practice · 2021Review
- The Incidence and Effect of Cytomegalovirus Disease on Mortality in Transplant Recipients and General Population: Real-world Nationwide Cohort Data.International journal of medical sciences · 2021Article
- Association between cytomegalovirus end-organ diseases and moderate-to-severe dementia: a population-based cohort study.BMC neurology · 2020Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundA latent cytomegalovirus (CMV) cause chronic inflammation through undesirable inflation of cell-mediated immune response. CMV immunoglobulin G has been associated with cardiovascular disease and type 1 diabetes mellitus. We evaluated impact of CMV diseases on new-onset type 2 diabetes mellitus (T2DM).
methodsFrom the Korean Health Insurance Review and Assessment Service claim database of entire population with 50 million, we retrieved 576 adult case group with CMV diseases diagnosed with International Statistical Classification of Diseases and Related-Health Problems 10th Revision (ICD-10) B25 code between 2010 and 2014 after exclusion of patients with T2DM to 2006. The 2,880 control patients without T2DM from 2006 to cohort entry point were selected between 2010 and 2014 by age, sex matching with case group. The subjects without new-onset T2DM were followed until 2015. T2DM, hypertension (HTN), dyslipidemia (DYS), and end-stage renal disease (ESRD) were coded as ICD-10.
resultsThe frequency of new-onset T2DM in case group was significantly higher than that in control (5.6% vs. 2.2%,
conclusionCMV diseases increase the patients' risk of developing T2DM.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.