Evidence map›Paper›PMID 30687792›Full record

ArticleWellcome open research2018

Lessons from the first clinical trial of a non-licensed vaccine among Ugandan adolescents: a phase II field trial of the tuberculosis candidate vaccine, MVA85A.

Anne Wajja, Milly Namutebi, Barbara Apule, Gloria Oduru, Samuel Kiwanuka, Mirriam Akello, Beatrice Nassanga, Joyce Kabagenyi, Juma Mpiima, Samantha Vermaak and 9 more

Open access · goldAbstract read
In one paragraph

Article in Wellcome open research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 4 institutions in 4 countries.

Anne WajjaMRC/UVRI and LSHTM Uganda Research Unit, Entebbe, Uganda.ORCID https://orcid.org/0000-0003-1711-4218
Milly NamutebiMRC/UVRI and LSHTM Uganda Research Unit, Entebbe, Uganda.
Barbara ApuleMRC/UVRI and LSHTM Uganda Research Unit, Entebbe, Uganda.
Gloria OduruMRC/UVRI and LSHTM Uganda Research Unit, Entebbe, Uganda.
Samuel KiwanukaMRC/UVRI and LSHTM Uganda Research Unit, Entebbe, Uganda.
Mirriam AkelloMRC/UVRI and LSHTM Uganda Research Unit, Entebbe, Uganda.
Beatrice NassangaMRC/UVRI and LSHTM Uganda Research Unit, Entebbe, Uganda.
Joyce KabagenyiMRC/UVRI and LSHTM Uganda Research Unit, Entebbe, Uganda.
Juma MpiimaVector Control Division, Ministry of Health of Uganda, Kampala, Uganda.
Samantha VermaakThe Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Alison LawrieThe Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Iman SattiThe Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Jaco VerweijLaboratory for Medical Microbiology and Immunology & Laboratory for Clinical Pathology,, St. Elisabeth Hospital, Tilburg, The Netherlands.
Stephen CoseMRC/UVRI and LSHTM Uganda Research Unit, Entebbe, Uganda.ORCID https://orcid.org/0000-0002-5156-037X
Jonathan LevinMRC/UVRI and LSHTM Uganda Research Unit, Entebbe, Uganda.
Pontiano KaleebuMRC/UVRI and LSHTM Uganda Research Unit, Entebbe, Uganda.
Edridah TukahebwaVector Control Division, Ministry of Health of Uganda, Kampala, Uganda.
Helen McShane *The Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.ORCID https://orcid.org/0000-0002-2126-5142
Alison M Elliott *MRC/UVRI and LSHTM Uganda Research Unit, Entebbe, Uganda.ORCID https://orcid.org/0000-0003-2818-9549
University of Cape Town · ZAUniversity of Oxford · GBMinistry of Health · UGElisabeth-TweeSteden Ziekenhuis · NL

Funding

Medical Research Council MC_UU_00027/1Medical Research Council MC_UU_00027/5Wellcome Trust
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdolescentsAfricaChallengesClinical trialsLessonsTuberculosisVaccines

Identifiers

PMID30687792
PMCPMC6338128
OpenAlexW2890375731

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.