Evidence map›Paper›PMID 30687643›Full record

ArticleFrontiers in cellular and infection microbiology2018

TLR3 Is a Negative Regulator of Immune Responses Against

Grasielle Pereira Jannuzzi, José Roberto Fogaça de Almeida, Gustavo P Amarante-Mendes, Lavínia Maria Dal'Mas Romera, Gilberto Hideo Kaihami, José Ronnie Vasconcelos, Camila Pontes Ferreira, Sandro Rogério de Almeida, Karen Spadari Ferreira

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

  1. Polymorphism in the Promoter Region of theFrontiers in immunology · 2020
    Trial
  2. Review
  3. Article
  4. Article
  5. Common virulence factors betweenCurrent research in microbial sciences · 2024
    Review
  6. Article
  7. Review
  8. Article
  9. Paracoccidioidomycosis Protective Immunity.Journal of fungi (Basel, Switzerland) · 2021
    Review
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Grasielle Pereira JannuzziDepartamento de Análises Clínicas, Faculdade de Ciências Farmacêuticas da Universidade de São Paulo, São Paulo, Brazil.
José Roberto Fogaça de AlmeidaDepartamento de Análises Clínicas, Faculdade de Ciências Farmacêuticas da Universidade de São Paulo, São Paulo, Brazil.
Gustavo P Amarante-MendesDepartamento de Imunologia, do Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, Brazil.
Lavínia Maria Dal'Mas RomeraDepartamento de Análises Clínicas, Faculdade de Ciências Farmacêuticas da Universidade de São Paulo, São Paulo, Brazil.
Gilberto Hideo KaihamiDepartamento de Química, Instituto de Química, Universidade de São Paulo, São Paulo, Brazil.
José Ronnie VasconcelosDepartamento de Biociências da Universidade Federal de São Paulo, São Paulo, Brazil.
Camila Pontes FerreiraCentro de Terapia Molecular e Celular do Departamento de Microbiologia, Imunologia e Parasitologia da Universidade Federal de São Paulo, São Paulo, Brazil.
Sandro Rogério de AlmeidaDepartamento de Análises Clínicas, Faculdade de Ciências Farmacêuticas da Universidade de São Paulo, São Paulo, Brazil.
Karen Spadari FerreiraDepartamento de Análises Clínicas, Faculdade de Ciências Farmacêuticas da Universidade de São Paulo, São Paulo, Brazil.
Universidade de São Paulo · BRUniversidade Federal de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Toll-like receptors (TLRs) comprise the best-characterized pattern-recognition receptor (PRR) family able to activate distinct immune responses depending on the receptor/adaptor set assembled. TLRs, such as TLR2, TLR4 and TLR9, and their signaling were shown to be important in

Indexed as

AnimalsBone MarrowCD8-Positive T-LymphocytesCytokinesDisease Models, AnimalGranzymesLungLymphocyte ActivationMacrophagesMaleMiceMice, Inbred C57BLMice, KnockoutParacoccidioidesParacoccidioidomycosisPerforinCytokinesGranzymesPerforinToll-Like Receptor 3CD8+T cellscytotoxicParacoccidioides brasiliensisparacoccidioidomycosisTLR3

Identifiers

PMID30687643
PMCPMC6335947
OpenAlexW2910468985

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.