Evidence map›Paper›PMID 30687624›Full record

ReviewGland surgery2018

Paradigm shift in the local treatment of breast cancer: mastectomy to breast conservation surgery.

Kowsi Murugappan, Apoorva Saboo, Lu Kuo, Owen Ung

Registry-linked trialAbstract readReview
In one paragraph

Review in Gland surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07539545 (A Comparative Study of Minimal Accessory-Incision-Assisted Endoscopic Breast-Conserving Surgery With Minimal Auxiliary Incisions Versus Conventional Open Breast-Conserving Surgery), which is not on this map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07539545 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

A Comparative Study of Minimal Accessory-Incision-Assisted Endoscopic Breast-Conserving Surgery With Minimal Auxiliary Incisions Versus Conventional Open Breast-Conserving Surgery: A National Multicenter, Open-Label, Randomized Controlled Trial (MECO-BCS)

TypeinterventionalSponsorDu ZhengguiRan2026 to 2032Enrolled1,366ConditionsBreast CancerArmsMinimal accessory-incision-assisted endoscopic breast-conserving surgery, Conventional open breast-conserving surgery
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Breast conservation surgery & oncoplasty in India - Current scenario.The Indian journal of medical research · 2021
    Review
  10. Article
  11. Observational
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kowsi MurugappanRoyal Brisbane Breast Surgery Unit, Department of General Surgery, RBWH, Brisbane, Australia.
Apoorva SabooRoyal Brisbane Breast Surgery Unit, Department of General Surgery, RBWH, Brisbane, Australia.
Lu KuoUniversity of Queensland, Brisbane, Australia.
Owen UngRoyal Brisbane Breast Surgery Unit, Department of General Surgery, RBWH, Brisbane, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There have been fundamental changes in the approach to breast cancer management over the last century but the primary objective of achieving oncological safety remains unchanged. This evolution is highlighted with a summary of the key evidences in support of the oncological safety of breast conserving surgery (BCS) in early breast cancer (EBC) management. We will also discuss the increasingly pivotal role that neoadjuvant chemotherapy (NACT) may play, in the local treatment of EBC and locally advanced breast cancer (LABC) and the long-term surgical and oncological outcomes.

Indexed as

breast conservation surgery (BCS)Mastectomyneoadjuvant chemotherapy (NACT)oncological safety

Identifiers

PMID30687624
PMCPMC6323252

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.