ArticleTranslational vision science & technology2019
The Utility of Frame Averaging for Automated Algorithms in Analyzing Retinal Vascular Biomarkers in AngioVue OCTA.
Article in Translational vision science & technology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Pseudoaveraging for denoising of OCT angiography: a deep learning approach for image quality enhancement in healthy and diabetic eyes.International journal of retina and vitreous · 2023Article
- Towards standardizing retinal optical coherence tomography angiography: a review.Light, science & applications · 2022Review
- Retinal alterations in patients with Lafora disease.American journal of ophthalmology case reports · 2021Article
- Optical Coherence Tomography Angiography in the Thirteen-Lined Ground Squirrel.Translational vision science & technology · 2021Article
- Automated Segmentation of Optical Coherence Tomography Angiography Images: Benchmark Data and Clinically Relevant Metrics.Translational vision science & technology · 2020Article
- Assessing the Influence of OCT-A Device and Scan Size on Retinal Vascular Metrics.Translational vision science & technology · 2020Article
- Approaches to quantify optical coherence tomography angiography metrics.Annals of translational medicine · 2020Review
- Visual Acuity Recovery After Macular Hole Closure Associated With Foveal Avascular Zone Change.Translational vision science & technology · 2020Article
- Microvasculature Segmentation and Intercapillary Area Quantification of the Deep Vascular Complex Using Transfer Learning.Translational vision science & technology · 2020Article
- Visual Acuity and Foveal Structure in Eyes with Fragmented Foveal Avascular Zones.Ophthalmology. Retina · 2020Article
- Quantitative optical coherence tomography angiography: A review.Experimental biology and medicine (Maywood, N.J.) · 2020Review
- Retinal vascular metrics difference by comparison of two image acquisition modes using a novel OCT angiography prototype.PloS one · 2020Article
- Within-subject assessment of foveal avascular zone enlargement in different stages of diabetic retinopathy usingBiomedical optics express · 2018Article
- Perfusion Deficits in Diabetes Without Retinopathy Localize to the Perivenular Deep Capillaries Near the Fovea on OCT Angiography.Ophthalmology scienceArticle
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Authors and funding
6 authors.
Funding
Abstract
purposeThis study proposes an optical coherence tomography angiography (OCTA) frame-averaging method and investigates the effects of the number of frames acquired and averaged on metrics quantifying the foveal avascular zone (FAZ), vessel morphology, and parafoveal intercapillary area (PICA).
methodsTen OCTA frames were acquired for each of the 19 subjects without known retinal disease using the AngioVue OCTA system. For each subject, acquired frames were ranked by an image quality metric. A subset of frames was then registered and averaged. The effects of the number of frames acquired and averaged on FAZ segmentation and metrics of FAZ geometry, vessel morphology, and PICA were analyzed.
resultsFrame averaging increased the accuracy of the automatically segmented FAZ region; for example, the absolute error in FAZ area decreased from 0.026 mm
conclusionsAveraging multiple OCTA frames using the Optovue AngioVue system reduced error in FAZ segmentation and improved the robustness of OCTA vessel morphology and perfusion metrics. The study demonstrated limited benefit in acquiring and averaging more than five frames. TRANSLATIONAL RELEVANCE: Averaging multiple OCTA frames improved the robustness of OCTA foveal biomarkers with limited benefit when averaging more than five frames.
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