Evidence map›Paper›PMID 30687551›Full record

ReviewJournal of nutrition and metabolism2018

Nutritional and Pharmacological Effects on Oxidative Stress in Soft Tissue and Bone Remodeling.

Benjamin M Savasky, David P Mascotti, Naren Patel, Edgardo Rodriguez-Collazo

Open access · goldAbstract readReview
In one paragraph

Review in Journal of nutrition and metabolism, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Benjamin M SavaskyUniversity Hospitals, 27100 Chardon Rd., Richmond Heights, OH 4414, USA.
David P MascottiJohn Carroll University, Department of Chemistry, 1 John Carroll Blvd., University Heights, OH 44118, USA.ORCID 0000-0003-1184-6784
Naren PatelFoot and Ankle Specialists of Ohio, 7482 Center St. Suite #100, Mentor, OH 44060, USA.
Edgardo Rodriguez-CollazoSt. Joseph Hospital, Department of Surgery, 875 N. Dearborn St. #400, Chicago, IL 60610, USA.
John Carroll University · USOrthopedic Foot & Ankle Center · USSt. Joseph Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oxidative damage is the causal link to a multitude of pathologies, such as diabetes, arthritis, neuropathy, heart disease, and asthma. These conditions affect hundreds of millions of people nationwide, and billions worldwide. Even in otherwise healthy individuals, oxidative stress is a natural byproduct of metabolism that is augmented in "healthy" activities such as athletics. In many disease states, the pharmacological agents used to treat these conditions can induce oxidative damage and vitamin depletion. It is underappreciated by many that many of the most common medications prescribed result in oxidative stress. Therefore, physicians need to carefully scrutinize which medications their patients are on before surgery and treatment and during the recovery stage to obtain optimal healing results. We provide a review of the current literature of how oxidative damage and inflammation are linked to bone damage, Charcot neuroarthropathy, delayed wound healing, diabetic complications, and delayed flap consolidation. Where available, antioxidant intervention literature is offered to offset these conditions.

Identifiers

PMID30687551
PMCPMC6327261
OpenAlexW2907237379

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.