ArticleJournal of ophthalmology2018
Pupil Size Associated with the Largest Iris Volume in Normal Chinese Eyes.
Article in Journal of ophthalmology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed.
- Experimental Assessment of Iris Water Content and Sex Differences in Mature Rabbits.bioRxiv : the preprint server for biology · 2026Article
- Generation of a human-induced pluripotent stem cell line from a retinitis pigmentosa patient carrying biallelic mutations in EYS gene.Human cell · 2026Article
- Impact of Acute Short-Term Hypobaric Hypoxia on Anterior Chamber Geometry.Journal of glaucoma · 2025Article
- Investigation of 3D iris morphology early alteration after implantable collamer lens implantation by using SS-OCT.Heliyon · 2025Article
- Ocular emergencies visits after corneal transplantation at a tertiary eye care hospital in Saudi Arabia.International ophthalmology · 2022Article
- Ocular morphologic traits in the American Cocker Spaniel may confer primary angle closure glaucoma susceptibility.Scientific reports · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo determine the range of pupil size that has the largest iris volume in normal eyes.
methods31 healthy adult Chinese volunteers underwent swept-source anterior segment OCT examination in both eyes. Pilocarpine 1% was instilled in a randomly selected eye (eye with induced miosis (ME)) of each participant to obtain iris volume (IV) measurements over a range of pupil sizes. OCT was performed prior to and one hour after pilocarpine in both ME and fellow eye (FE). Iris volume (IV), anterior chamber volume (ACV), anterior chamber depth (ACD), and pupil size (PS) were recorded. A scatter plot was used to depict the association between each pupil size and IV.
resultsThe pupillary sizes for which IV was recorded in ME and FE ranged from 1.161 mm to 6.665 mm. The mean IV increased with miosis in both ME and FE; in 13 eyes, IV decreased with a decrease in pupillary size. PS between 3.812 and 6.665 mm was associated with an increase in IV, while PS between 3.159 and 5.54 mm was associated with a decrease. The relationship between PS and IV was in the shape of a downward parabola and was modeled using a quadratic equation (
conclusionsThe relationship between PS and IV in this study was in the shape of a downward parabola. The largest IV was recorded at a pupillary size between 3 and 4 mm. This trial is registered with ChiCTR-ROC-17013572.
Identifiers
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Registered trials
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