ReviewJournal of thoracic disease2018
Systemic hypertension in obstructive sleep apnea.
Review in Journal of thoracic disease, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.
- Effects of Exercise on Patients with Obstructive Sleep Apnea: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2022Pooled it
- Association of obstructive sleep apnoea with long-term cardiovascular events in patients with acute coronary syndrome with or without hypertension: insight from the OSA-ACS project.BMJ open respiratory research · 2023Trial
- Arterial Stiffness in Patients with Obstructive Sleep Apnea and Hypertension: A Narrative Review.Medical sciences (Basel, Switzerland) · 2026Review
- The association between cardiovascular health, measured using Life's Essential 8, and obstructive sleep apnea: a cross-sectional and Mendelian randomization study.American journal of translational research · 2026Article
- A composite score of polygraphic oximetry parameters predicts left ventricular hypertrophy in patients with obstructive sleep apnoea.ERJ open research · 2025Article
- Effects of obstructive sleep apnea on nocturnal changes in blood pressure - a retrospective study.Hypertension research : official journal of the Japanese Society of Hypertension · 2025Article
- The diagnostic value of polysomnography in obstructive sleep apnea-hypopnea syndrome patients with hypertension and secondary atherosclerosis.American journal of translational research · 2025Article
- The association between triglyceride glucose index and the risk of cardiovascular disease in obstructive sleep apnea.Sleep & breathing = Schlaf & Atmung · 2024Article
- Mineralocorticoid receptor antagonists in adults with resistant hypertension and obstructive sleep apnoea.Australian prescriber · 2024Article
- Impact of Obstructive Sleep Apnea and Sympathetic Nervous System on Cardiac Health: A Comprehensive Review.Journal of cardiovascular development and disease · 2024Review
- Metabolic Crossroads: Unveiling the Complex Interactions between Obstructive Sleep Apnoea and Metabolic Syndrome.International journal of molecular sciences · 2024Review
- Consensus Statements among European Sleep Surgery Experts on Snoring and Obstructive Sleep Apnea: Part 1 Definitions and Diagnosis.Journal of clinical medicine · 2024Article
- Obstructive sleep apnoea heterogeneity and cardiovascular disease.Nature reviews. Cardiology · 2023Review
- Obstructive Sleep Apnea and Cardiovascular Disease: Where Do We Stand?Anatolian journal of cardiology · 2023Review
- 10-Year Risk for Cardiovascular Disease Associated with COMISA (Co-Morbid Insomnia and Sleep Apnea) in Hypertensive Subjects.Life (Basel, Switzerland) · 2023Article
- Bidirectional relationships of comorbidity with obstructive sleep apnoea.European respiratory review : an official journal of the European Respiratory Society · 2022Review
- Relationships Between Obstructive Sleep Apnea and Cardiovascular Disease: A Bibliometric Analysis (2010-2021).Medical science monitor : international medical journal of experimental and clinical research · 2022Article
- Sleep apnea and autonomic dysfunction in patients with dementia.Frontiers in neuroscience · 2022Review
- Smoking and Obstructive Sleep Apnea: Is There An Association between These Cardiometabolic Risk Factors?-Gender Analysis.Medicina (Kaunas, Lithuania) · 2021Article
- Sleep disorders in Alzheimer's disease: the predictive roles and potential mechanisms.Neural regeneration research · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There is consistent epidemiological evidence that sleep disordered breathing and systemic arterial hypertension are deeply associated, being linked through a bidirectional complex interaction among multiple mechanisms including autonomic nervous system alterations, inflammation, hormonal and hemodynamic components, sleep alterations. However there are several unanswered questions not only from a pathophysiological perspective, but also regarding the effects of obstructive sleep apnea (OSA) treatment on arterial blood pressure values. At present, while many studies have supported the possibility to obtain at least a small blood pressure reduction with OSA treatment, in particular in hypertensive patients, large trials have not clearly confirmed a significant anti-hypertensive effect, nor a beneficial effect of this intervention on cardiovascular endpoints including cardiovascular mortality. Aim of the present review article is to address the relationship between OSA and hypertension in the light of the latest evidence in the field. Moreover we will discuss research topics which need to be investigated in the future, in order to better clarify still pending issues with the aim of obtaining an early diagnosis, a more suitable phenotyping including comorbidities, and better strategies to improve patients' compliance and adherence to treatment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.