Evidence map›Paper›PMID 30687528›Full record

ArticleCurrent health sciences journal

Blood Coagulation Following an Acute Ischemic Stroke.

M D Sfredel, E Burada, B Cătălin, V Dinescu, G Târtea, M Iancău, E Osiac

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In one paragraph

Article in Current health sciences journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

M D SfredelDepartment of Physiology, University of Medicine and Pharmacy from Craiova, Romania.
E BuradaDepartment of Physiology, University of Medicine and Pharmacy from Craiova, Romania.
B CătălinDepartment of Physiology, University of Medicine and Pharmacy from Craiova, Romania.
V DinescuDepartment of Physiology, University of Medicine and Pharmacy from Craiova, Romania.
G TârteaDepartment of Physiology, University of Medicine and Pharmacy from Craiova, Romania.
M IancăuDepartment of Physiology, University of Medicine and Pharmacy from Craiova, Romania.
E OsiacDepartment of Biophysics, University of Medicine and Pharmacy from Craiova, Romania.
University of Medicine and Pharmacy of Craiova · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveHemostasis is a complex physiological process that stops bleeding at the site of a vascular injury. Although the majority of vascular accidents are ischemic, the role of hypercoagulable state and stroke needs further investigation. MATERIALS AND

methodsFresh whole blood was taken from 61 acute ischemic stroke patients and compared to 18 healthy subjects and investigated with optical coherence tomography imaging after initiating coagulation. We used an OCT1300SS system (Thorlabs) and did 3D scans. We then processed the images with ImageJ. For each image mean, integrated density, skewness and kurtosis of gray values were analyzed.

resultsMean gray value and integrated intensity of sampled data showed an intrinsic difference detected with OCT. This difference was further confirmed by the data distribution analysis.

conclusionsResults suggest, that normal blood coagulation, is not a random reaction while in the case of stroke patients, the relatively symmetrical distribution of gray values brings coagulation closer randomized process.

Indexed as

cerebral ischemiacoagulationoptical coherence tomography

Identifiers

PMID30687528
PMCPMC6320462
OpenAlexW2985659034

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.