Evidence map›Paper›PMID 30687385›Full record

ArticleFrontiers in genetics2018

Genome-Wide Variation, Candidate Regions and Genes Associated With Fat Deposition and Tail Morphology in Ethiopian Indigenous Sheep.

Abulgasim Ahbara, Hussain Bahbahani, Faisal Almathen, Mohammed Al Abri, Mukhtar Omar Agoub, Ayelle Abeba, Adebabay Kebede, Hassan Hussein Musa, Salvatore Mastrangelo, Fabio Pilla and 3 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in genetics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 1 pooled it
11.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 1 synthesis or guideline pooled it, 102 citations in OpenAlex.

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  20. Recent advances in the genomic resources for sheep.Mammalian genome : official journal of the International Mammalian Genome Society · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 11 institutions in 8 countries.

Abulgasim AhbaraSchool of Life Sciences, University of Nottingham, Nottingham, United Kingdom.
Hussain BahbahaniDepartment of Biological Sciences, Faculty of Science, Kuwait University, Safat, Kuwait.
Faisal AlmathenDepartment of Veterinary Public Health and Animal Husbandry, College of Veterinary Medicine, King Faisal University, Al-Ahsa, Saudi Arabia.
Mohammed Al AbriDepartment of Animal and Veterinary Sciences, College of Agriculture and Marine Sciences, Sultan Qaboos University, Muscat, Oman.
Mukhtar Omar AgoubAgricultural Research Center, Misurata, Libya.
Ayelle AbebaDebre Berhan Research Centre, Debre Berhan, Ethiopia.
Adebabay KebedeAmhara Regional Agricultural Research Institute, Bahir Dar, Ethiopia.
Hassan Hussein MusaFaculty of Medical Laboratory Sciences, University of Khartoum, Khartoum, Sudan.
Salvatore MastrangeloDipartimento di Scienze Agrarie e Forestali, Viale delle Scienze, Università Palermo, Palermo, Italy.
Fabio PillaDipartimento Agricoltura, Ambiente e Alimenti, Università degli Studi del Molise, Campobasso, Italy.
Elena CianiDipartimento di Bioscienze, Biotecnologie e Biofarmaceutica, Università degli Studi di Bari "Aldo Moro ", Bari, Italy.
Olivier HanotteSchool of Life Sciences, University of Nottingham, Nottingham, United Kingdom.
Joram M MwacharoSmall Ruminant Genomics, International Center for Agricultural Research in the Dry Areas (ICARDA), Addis Ababa, Ethiopia.
University of Nottingham · GBAmhara Regional Agricultural Research Institute · ETDebre Berhan University · ETKing Faisal University · SAKuwait University · KWMisurata University · LYSultan Qaboos University · OMUniversity of Bari Aldo Moro · ITUniversity of Khartoum · SDUniversity of Molise · ITUniversity of Palermo · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Variations in body weight and in the distribution of body fat are associated with feed availability, thermoregulation, and energy reserve. Ethiopia is characterized by distinct agro-ecological and human ethnic farmer diversity of ancient origin, which have impacted on the variation of its indigenous livestock. Here, we investigate autosomal genome-wide profiles of 11 Ethiopian indigenous sheep populations using the Illumina Ovine 50 K SNP BeadChip assay. Sheep from the Caribbean, Europe, Middle East, China, and western, northern and southern Africa were included to address globally, the genetic variation and history of Ethiopian populations. Population relationship and structure analysis separated Ethiopian indigenous fat-tail sheep from their North African and Middle Eastern counterparts. It indicates two main genetic backgrounds and supports two distinct genetic histories for African fat-tail sheep. Within Ethiopian sheep, our results show that the short fat-tail sheep do not represent a monophyletic group. Four genetic backgrounds are present in Ethiopian indigenous sheep but at different proportions among the fat-rump and the long fat-tail sheep from western and southern Ethiopia. The Ethiopian fat-rump sheep share a genetic background with Sudanese thin-tail sheep. Genome-wide selection signature analysis identified eight putative candidate regions spanning genes influencing growth traits and fat deposition (

Indexed as

admixtureAfricafat-tailOvis ariesthin-tail

Identifiers

PMID30687385
PMCPMC6334744
OpenAlexW2909768242

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.