Evidence map›Paper›PMID 30687322›Full record

ArticleFrontiers in immunology2018

Myosin 1F Regulates M1-Polarization by Stimulating Intercellular Adhesion in Macrophages.

Zayda L Piedra-Quintero, Carolina Serrano, Nicolás Villegas-Sepúlveda, José L Maravillas-Montero, Sandra Romero-Ramírez, Mineko Shibayama, Oscar Medina-Contreras, Porfirio Nava, Leopoldo Santos-Argumedo

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 57 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Zayda L Piedra-QuinteroDepartment of Molecular Biomedicine, Cinvestav Zacatenco, Mexico City, Mexico.
Carolina SerranoDepartment of Physiology, Biophysics and Neurosciences, Cinvestav Zacatenco, Mexico City, Mexico.
Nicolás Villegas-SepúlvedaDepartment of Molecular Biomedicine, Cinvestav Zacatenco, Mexico City, Mexico.
José L Maravillas-MonteroResearch Support Network, Universidad Nacional Autónoma de México and Instituto Nacional de Ciencias Médicas y Nutrición "Salvador Zubirán", Mexico City, Mexico.
Sandra Romero-RamírezResearch Support Network, Universidad Nacional Autónoma de México and Instituto Nacional de Ciencias Médicas y Nutrición "Salvador Zubirán", Mexico City, Mexico.
Mineko ShibayamaDepartment of Infectomics and Molecular Pathogenesis, Cinvestav Zacatenco, Mexico City, Mexico.
Oscar Medina-ContrerasImmunology and Proteomics Laboratory, Mexico Children's Hospital Federico Gómez, Mexico City, Mexico.
Porfirio NavaDepartment of Physiology, Biophysics and Neurosciences, Cinvestav Zacatenco, Mexico City, Mexico.
Leopoldo Santos-ArgumedoDepartment of Molecular Biomedicine, Cinvestav Zacatenco, Mexico City, Mexico.
Center for Research and Advanced Studies of the National Polytechnic Institute · MXHospital Infantil de México Federico Gómez · MXInstituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán · MXUniversidad Nacional Autónoma de México · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intestinal macrophages are highly mobile cells with extraordinary plasticity and actively contribute to cytokine-mediated epithelial cell damage. The mechanisms triggering macrophage polarization into a proinflammatory phenotype are unknown. Here, we report that during inflammation macrophages enhance its intercellular adhesion properties in order to acquire a M1-phenotype. Using

Indexed as

Macrophage ActivationAnimalsCell Line, TumorColitis, UlcerativeCytoskeletonDextran SulfateDisease Models, AnimalHumansIntegrin alphaVbeta3Interleukin-1betaMacrophagesMaleMiceMice, Inbred C57BLMice, KnockoutMyosin Type IDextran SulfateIL1B protein, mouseIntegrin alphaVbeta3Interleukin-1betaMyo1f protein, mouseMyosin Type IAkt/mTOR/STAT signalinginflammationintercellular adhesionM1-polarizationmyosin 1F

Identifiers

PMID30687322
PMCPMC6335276
OpenAlexW2911147142

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.