Evidence map›Paper›PMID 30687313›Full record

ArticleFrontiers in immunology2018

The First Step in Adoptive Cell Immunotherapeutics: Assuring Cell Delivery via Glycoengineering.

Robert Sackstein

Abstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Review
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  10. Sweet Immune Checkpoint Targets to Enhance T Cell Therapy.Journal of immunology (Baltimore, Md. : 1950) · 2022
    Review
  11. Review
  12. Article
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  18. Chimeric Antigen Receptor-T Cells for Targeting Solid Tumors: Current Challenges and Existing Strategies.BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy · 2019
    Review
  19. I-branched carbohydrates as emerging effectors of malignant progression.Proceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Robert SacksteinDepartment of Translational Medicine, Herbert Wertheim College of Medicine, Florida International University, Miami, FL, United States.

Funding

REGULATION OF LACTOSAMINYL GLYCAN BIOSYNTHESIS IN HEMATOPOIETIC CELLSP01HL107146 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI LAU, JOSEPH TY · 2011 to 2017
$17.7M
NHLBI NIH HHS P01 HL107146
6 · The paper itself

Abstract

Despite decades of intensive attention directed to creation of genetically altered cells (e.g., as in development of chimeric antigen receptor (CAR) T-cells) and/or to achieve requisite

Indexed as

E-SelectinGlycomicsGlycoproteinsHumansImmunotherapy, AdoptiveLewis X AntigenLigandsNeoplasmsReceptors, Chimeric AntigenT-LymphocytesTranslational Research, BiomedicalE-SelectinGlycoproteinsLewis X AntigenLigandsReceptors, Chimeric Antigenadoptive cell therapyCAR T cellE-selectin ligandfucosyltransferaseGPSsialyl Lewis XsLeXtranslational glycobiology

Identifiers

PMID30687313
PMCPMC6336727

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.