Evidence map›Paper›PMID 30687304›Full record

ArticleFrontiers in immunology2018

Immunological Homeostasis at the Ovine Placenta May Reflect the Degree of Maternal Fetal Interaction.

Sean R Wattegedera, Laura E Doull, Mariya I Goncheva, Nicholas M Wheelhouse, Donna M Watson, Julian Pearce, Julio Benavides, Javier Palarea-Albaladejo, Colin J McInnes, Keith Ballingall and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. The Immune Response in the Uteri and Placentae ofPathogens (Basel, Switzerland) · 2023
    Article
  4. Article
  5. Efficacy of TwoVaccines · 2021
    Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 3 countries.

Sean R WattegederaVaccines Department, Moredun Research Institute, Penicuik, United Kingdom.
Laura E DoullCentre for Dementia Prevention, University of Edinburgh, Edinburgh, United Kingdom.
Mariya I GonchevaDepartment of Microbiology and Immunology, University of Western Ontario, London, ON, Canada.
Nicholas M WheelhouseSchool of Applied Sciences, Napier University, Edinburgh, United Kingdom.
Donna M WatsonTriveritas Ltd., Brampton, United Kingdom.
Julian PearceUniversity College London Hospital, London, United Kingdom.
Julio BenavidesInstituto de Ganadería de Montaña (IGM), León, Spain.
Javier Palarea-AlbaladejoBiomathematics and Statistics Scotland, Edinburgh, United Kingdom.
Colin J McInnesVaccines Department, Moredun Research Institute, Penicuik, United Kingdom.
Keith BallingallVaccines Department, Moredun Research Institute, Penicuik, United Kingdom.
Gary EntricanVaccines Department, Moredun Research Institute, Penicuik, United Kingdom.
Moredun Research Institute · GBBiomathematics and Statistics Scotland · GBEdinburgh Napier University · GBInstituto de Ganadería de Montaña · ESUniversity College Hospital · GBUniversity of Edinburgh · GBWestern University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Successful mammalian pregnancies are a result of complex physiological, endocrinological, and immunological processes that combine to create an environment where the mother is tolerant to the semi-allogeneic fetus. Our knowledge of the mechanisms that contribute to maternal tolerance is derived mainly from human and murine studies of haemochorial placentation. However, as this is the most invasive type of placentation it cannot be assumed that identical mechanisms apply to the less invasive epitheliochorial placentation found in other species such as ruminants. Here, we examine three features associated with reproductive immune regulation in a transformed ovine trophoblast cell line and

Indexed as

AnimalsBiomarkersCell LineFemaleGene ExpressionHomeostasisImmunophenotypingMajor Histocompatibility ComplexMaternal-Fetal ExchangeNatural Cytotoxicity Triggering Receptor 1PhylogenyPlacentaPregnancySequence Analysis, DNASheepTrophoblastsBiomarkersNatural Cytotoxicity Triggering Receptor 1indoleamine 2,3 dioxygenase-1major histocompatibility complexovinesynepitheliochorial placentationtrophoblast

Identifiers

PMID30687304
PMCPMC6334339
OpenAlexW2904198154

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.