Evidence map›Paper›PMID 30687285›Full record

ArticleFrontiers in microbiology2018

Perspectives of Phage Therapy in Non-bacterial Infections.

Andrzej Górski, Paul L Bollyky, Maciej Przybylski, Jan Borysowski, Ryszard Międzybrodzki, Ewa Jończyk-Matysiak, Beata Weber-Dąbrowska

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
8.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 62 citations in OpenAlex.

  1. Review
  2. Antibiotic Resistance ofPharmaceuticals (Basel, Switzerland) · 2025
    Review
  3. Article
  4. Article
  5. Article
  6. The Role of the Cutaneous Mycobiome in Atopic Dermatitis.Journal of fungi (Basel, Switzerland) · 2022
    Review
  7. Review
  8. Article
  9. Considerations for the Use of Phage Therapy in Clinical Practice.Antimicrobial agents and chemotherapy · 2022
    Review
  10. Article
  11. Article
  12. Review
  13. Gut Microbes and Eye Disease.Ophthalmic research · 2022
    Review
  14. Phage therapy in the Covid-19 era: Advantages over antibiotics.Current research in microbial sciences · 2022
    Review
  15. Review
  16. Article
  17. Review
  18. Article
  19. Gut microbiota in human metabolic health and disease.Nature reviews. Microbiology · 2021
    Review
  20. Phages in the fight against COVID-19?Future microbiology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Andrzej GórskiLudwik Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wrocław, Poland.
Paul L BollykyDivision of Infectious Diseases, Department of Medicine, Stanford University Medical School, Stanford, CA, United States.
Maciej PrzybylskiDepartment of Medical Microbiology, Medical University of Warsaw, Warsaw, Poland.
Jan BorysowskiDepartment of Clinical Immunology, Medical University of Warsaw, Warsaw, Poland.
Ryszard MiędzybrodzkiLudwik Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wrocław, Poland.
Ewa Jończyk-MatysiakLudwik Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wrocław, Poland.
Beata Weber-DąbrowskaLudwik Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wrocław, Poland.
Medical University of Warsaw · PLPolish Academy of Sciences · PLStanford University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While the true value of phage therapy (PT) in human bacterial infections still awaits formal confirmation by clinical trials, new data have been accumulating indicating that in the future PT may be applied in the treatment of non-bacterial infections. Thus, "phage guests" may interact with eukaryotic cells and such interactions with cells of the immune system may protect human health (Guglielmi, 2017) and cause clinically useful immunomodulatory and anti-inflammatory effects when administered for therapeutic purposes (Górski et al., 2017; Van Belleghem et al., 2017). Recently, a vision of how these effects could translate into advances in novel means of therapy in a variety of human pathologies secondary to immune disturbances and allergy was presented (Górski et al., 2018a). In this article we present what is currently known about anti-microbial effects of phage which are not directly related to their antibacterial action and how these findings could be applied in the future in treatment of viral and fungal infections.

Indexed as

drug repurposingfungal infectionphagephage therapyviral infection

Identifiers

PMID30687285
PMCPMC6333649
OpenAlexW2909133443

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.