Evidence map›Paper›PMID 30687250›Full record

ArticleFrontiers in microbiology2018

A Novel Bacteriophage Lysin-Human Defensin Fusion Protein Is Effective in Treatment of

Zhong Peng, Shaohui Wang, Mussie Gide, Duolong Zhu, Hiran Malinda Lamabadu Warnakulasuriya Patabendige, Chunhui Li, Jianfeng Cai, Xingmin Sun

Abstract read
In one paragraph

Article in Frontiers in microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Review
  11. Phage therapy forFrontiers in immunology · 2022
    Review
  12. Review
  13. Review
  14. Review
  15. Article
  16. Review
  17. Characterization of an Endolysin TargetingInternational journal of molecular sciences · 2021
    Article
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zhong PengDepartment of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, FL, United States.
Shaohui WangDepartment of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, FL, United States.
Mussie GideDepartment of Chemistry, University of South Florida, Tampa, FL, United States.
Duolong ZhuDepartment of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, FL, United States.
Hiran Malinda Lamabadu Warnakulasuriya PatabendigeDepartment of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, FL, United States.
Chunhui LiDepartment of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, FL, United States.
Jianfeng CaiDepartment of Chemistry, University of South Florida, Tampa, FL, United States.
Xingmin SunDepartment of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, FL, United States.

Funding

Multivalent vaccines against Clostridium difficile infectionR01AI132711 · NIAID · UNIVERSITY OF SOUTH FLORIDA · PI Xingmin Sun, Shifeng Wang · 2017 to 2026
$3.3M
Requesting HPLC for the project of "Alpha-AApeptides as a Novel Class of Antimicrobial Biomaterials"R01GM112652 · NIGMS · UNIVERSITY OF SOUTH FLORIDA · PI CAI, JIANFENG · 2015 to 2019
$1.5M
Signaling pathway of TNF-alpha production and Clostridium difficile infection (CDK01DK092352 · NIDDK · UNIVERSITY OF SOUTH FLORIDA · PI SUN, XINGMIN · 2012 to 2016
$470k
Multivalent Bacillus mucosal vaccines against Clostridium difficile infectionR21AI113470 · NIAID · UNIVERSITY OF SOUTH FLORIDA · PI SUN, XINGMIN · 2015 to 2016
$438k
The role of tumor progression locus 2 (TPL2) in the pathogenesis of Clostridium difficile infection (CDI)R03DK112004 · NIDDK · UNIVERSITY OF SOUTH FLORIDA · PI SUN, XINGMIN · 2017 to 2018
$154k
NIAID NIH HHS R01 AI132711NIAID NIH HHS R21 AI113470NIDDK NIH HHS K01 DK092352NIDDK NIH HHS R03 DK112004NIGMS NIH HHS R01 GM112652
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Clostridioides difficile infectionlysin-human defensin fusion proteinlytic activitynovel bacteriophagetreatment

Identifiers

PMID30687250
PMCPMC6336692

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.