Evidence map›Paper›PMID 30687091›Full record

ArticleFrontiers in pharmacology2018

Zolpidem Activation of Alpha 1-Containing GABA

Elena Neumann, Uwe Rudolph, Daniel E Knutson, Guanguan Li, James M Cook, Harald Hentschke, Bernd Antkowiak, Berthold Drexler

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.5field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

  1. Recovery from disorders of consciousness: Lesions and GABAergic modulation in a biologically inspired spiking neural network.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Article
  3. Article
  4. Review
  5. Z-Drugs in the Environment: A Review.Molecules (Basel, Switzerland) · 2026
    Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Regulation of GABATrends in neurosciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Elena NeumannExperimental Anesthesiology Section, Department of Anesthesiology and Intensive Care, Eberhard Karls Universität Tübingen, Tübingen, Germany.
Uwe RudolphDepartment of Comparative Biosciences, College of Veterinary Medicine, University of Illinois at Urbana-Champaign, Urbana, IL, United States.
Daniel E KnutsonDepartment of Chemistry and Biochemistry, University of Wisconsin-Milwaukee, Milwaukee, WI, United States.
Guanguan LiDepartment of Chemistry and Biochemistry, University of Wisconsin-Milwaukee, Milwaukee, WI, United States.
James M CookDepartment of Chemistry and Biochemistry, University of Wisconsin-Milwaukee, Milwaukee, WI, United States.
Harald HentschkeExperimental Anesthesiology Section, Department of Anesthesiology and Intensive Care, Eberhard Karls Universität Tübingen, Tübingen, Germany.
Bernd AntkowiakExperimental Anesthesiology Section, Department of Anesthesiology and Intensive Care, Eberhard Karls Universität Tübingen, Tübingen, Germany.
Berthold DrexlerExperimental Anesthesiology Section, Department of Anesthesiology and Intensive Care, Eberhard Karls Universität Tübingen, Tübingen, Germany.
University of Tübingen · DEUniversity of Wisconsin–Milwaukee · USBernstein Center for Computational Neuroscience Tübingen · DEUniversity of Illinois Urbana-Champaign · US

Funding

A GABA Pathway to Faster Acting AntidepressantsR01MH095905 · NIMH · MCLEAN HOSPITAL · PI RUDOLPH, UWE · 2012 to 2016
$2.0M
Design of New Therapeutic Agents to Treat SchizophreniaR01MH096463 · NIMH · UNIVERSITY OF WISCONSIN MILWAUKEE · PI COOK, JAMES M · 2013 to 2017
$1.9M
Regional actions of general anesthetics in inhibitory hippocampal networksR01GM086448 · NIGMS · MCLEAN HOSPITAL · PI RUDOLPH, UWE · 2009 to 2012
$1.9M
Synthesis of Alpha2/Alpha3 GABA Agonists to Treat Neuropathic PainR01NS076517 · NINDS · UNIVERSITY OF WISCONSIN MILWAUKEE · PI COOK, JAMES M · 2012 to 2015
$1.3M
NIGMS NIH HHS R01 GM086448NIMH NIH HHS R01 MH095905NIMH NIH HHS R01 MH096463NINDS NIH HHS R01 NS076517
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

benzodiazepineselectrophysiologyGABAA receptor subtypesGABAA receptor subtype specific drugsneocortexneocortical activityzolpidem

Identifiers

PMID30687091
PMCPMC6333667
OpenAlexW2910108522

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.