ArticleCase reports in oncology
Rare Case of Intracardiac Renal Cell Carcinoma Metastasis with Response to Nivolumab: Case Report and Literature Review.
Article in Case reports in oncology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 14 citations in OpenAlex.
- Safety and efficacy of immune checkpoint therapy for the treatment of patients with cardiac metastasis: a multicenter international retrospective study.Journal for immunotherapy of cancer · 2025Article
- Right atrial metastasis after renal cell carcinoma operation: a case report.AME case reports · 2025Article
- A case of surgical treatment for recurrence of right ventricular metastasis due to renal cell carcinoma after molecular targeted therapy.Surgical case reports · 2024Article
- Metastatic Renal Cell Carcinoma Presenting as an Intracardiac Tumour Without Involving the Inferior Vena Cava.Cureus · 2023Article
- Cardiac Metastasis From Renal Cell Carcinoma.Cureus · 2023Article
- Successful long-term management of metastatic clear cell renal cell carcinoma with nivolumab: a case report and literature review.Ecancermedicalscience · 2023Article
- Cardiac metastasis from small cell lung cancer origin: A case report and review of the literature.Cancer reports (Hoboken, N.J.) · 2022Review
- Renal Cell Carcinoma Metastasis to the Left Atrium.Texas Heart Institute journal · 2022Article
- Renal Cell Carcinoma with Cardiac Metastases: A Case Report and Review of the Literature.Journal of kidney cancer and VHL · 2022Article
- Renal Cell Carcinoma With Cardiac Metastases.World journal of oncology · 2021Article
- Robust response to nivolumab in patient with renal cell carcinoma inferior vena cava tumour thrombus.BMJ case reports · 2019Article
- Renal Cell Carcinoma Metastasizing to Left Atrium With Coronary Sinus Invasion: A Rare Site of Metastasis Mimicking Myxoma.Frontiers in oncology · 2019Article
- Efficacy of Nivolumab Plus Ipilimumab in a Patient With Renal Cell Carcinoma Concomitant With Cardiac Metastasis: A Case Report.In vivo (Athens, Greece)Article
Corrections and comments
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Authors and funding
10 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Intracardiac metastases in the absence of inferior vena cava involvement is a rare occurrence in patients with metastatic renal cell carcinoma (mRCC). There is limited evidence regarding the efficacy and safety of standard treatment modalities for mRCC patients with intracardiac metastases. Presence of intracardiac metastases is known to indicate poor prognosis and may potentially increase risk of treatment-related complications. Recent advances in RCC management have integrated nivolumab, a programmed death-1 (PD-1) receptor inhibitor, as a preferred treatment option in the second-line setting after failure of prior anti-angiogenic therapy; or in combination with ipilimumab, an anti-Cytotoxic T-lymphocyte antigen-4 antibody as first-line therapy for intermediate to poor risk patients with mRCC. The efficacy and toxicity of nivolumab in patients with mRCC and intracardiac metastases has never been reported previously. We herein present the first reported case of mRCC with intracardiac metastasis and a resultant excellent response to nivolumab treatment and discuss the imaging techniques and treatment options for this rare presentation.
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