Evidence map›Paper›PMID 30687027›Full record

ArticleFrontiers in systems neuroscience2018

Locus Coeruleus Optogenetic Light Activation Induces Long-Term Potentiation of Perforant Path Population Spike Amplitude in Rat Dentate Gyrus.

Meghan A L Quinlan, Vanessa M Strong, Darlene M Skinner, Gerard M Martin, Carolyn W Harley, Susan G Walling

Open access · goldAbstract read
In one paragraph

Article in Frontiers in systems neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 37 citations in OpenAlex.

  1. Review
  2. Oppositional and competitive instigation of hippocampal synaptic plasticity by the VTA and locus coeruleus.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  3. Review
  4. Bilateral Optogenetic Stimulation of the Olfactory Bulb of OMP-ChIEF Mice.Methods in molecular biology (Clifton, N.J.) · 2025
    Article
  5. Atrophy links lower novelty-related locus coeruleus connectivity to cognitive decline in preclinical AD.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
    Article
  6. Review
  7. Article
  8. Frequency Specific Optogenetic Stimulation of the Locus Coeruleus Induces Task-Relevant Plasticity in the Motor Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  9. Article
  10. Article
  11. Advances in the Electrophysiological Recordings of Long-Term Potentiation.International journal of molecular sciences · 2023
    Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Effects of Exercise on Long-Term Potentiation in Neuropsychiatric Disorders.Advances in experimental medicine and biology · 2020
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Meghan A L QuinlanBehavioural Neuroscience Group, Department of Psychology, Memorial University of Newfoundland, St. John's, NL, Canada.
Vanessa M StrongBehavioural Neuroscience Group, Department of Psychology, Memorial University of Newfoundland, St. John's, NL, Canada.
Darlene M SkinnerBehavioural Neuroscience Group, Department of Psychology, Memorial University of Newfoundland, St. John's, NL, Canada.
Gerard M MartinBehavioural Neuroscience Group, Department of Psychology, Memorial University of Newfoundland, St. John's, NL, Canada.
Carolyn W HarleyBehavioural Neuroscience Group, Department of Psychology, Memorial University of Newfoundland, St. John's, NL, Canada.
Susan G WallingBehavioural Neuroscience Group, Department of Psychology, Memorial University of Newfoundland, St. John's, NL, Canada.
Memorial University of Newfoundland · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Norepinephrine (NE) in dentate gyrus (DG) produces NE-dependent long-term potentiation (NE-LTP) of the perforant path-evoked potential population spike both

Indexed as

dentate gyrushippocampuslocus coeruleuslong-term potentiationnorepinephrineoptogeneticperforant pathshort-term potentiation

Identifiers

PMID30687027
PMCPMC6333706
OpenAlexW2909736334

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.