ArticleFrontiers in neuroscience2018
Autism Pathogenesis: The Superior Colliculus.
Article in Frontiers in neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 35 citations in OpenAlex.
- Postnatal Iron Supplementation Fails to Fully Rescue Brain Metal and Transcriptional Defects Caused by Nutrition-Based Gestational Iron Deficiency.The Journal of nutrition · 2026Article
- Layers of Social Meaning: Innate, Acquired, and Deliberative Levels of Referential Signal Processing.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Review
- Opposite sides of different coins: near-diametrical opposition of physiological indices of reduced accuracy of face emotion recognition in schizophrenia and autism spectrum disorders.Frontiers in neuroimaging · 2026Article
- Behavioral techniques for controlling visual stimuli to modulate visual processing in the brain and their implementation in augmented reality technology.Frontiers in neuroscience · 2026Review
- Global motion coherent deficits in individuals with autism spectrum disorder and their family members are associated with retinal function.Scientific reports · 2025Article
- Antifragile control systems in neuronal processing: a sensorimotor perspective.Biological cybernetics · 2025Review
- Article
- Hidden social and emotional competencies in autism spectrum disorders captured through the digital lens.Frontiers in psychiatry · 2025Article
- Mesenchymal Stem Cell-Induced Neuroprotection in Pediatric Neurological Diseases: Recent Update of Underlying Mechanisms and Clinical Utility.Applied biochemistry and biotechnology · 2024Review
- Article
- The Use of CGH Arrays for Identifying Copy Number Variations in Children with Autism Spectrum Disorder.Brain sciences · 2024Article
- Involvement of the Superior Colliculus in SIDS Pathogenesis.Biomedicines · 2023Article
- Valproic acid affects neurogenesis during early optic tectum development in zebrafish.Biology open · 2023Article
- Simulating developmental diversity: Impact of neural stochasticity on atypical flexibility and hierarchy.Frontiers in psychiatry · 2023Article
- Exploring the Social Environment with the Eyes: A Review of the Impact of Facial Stimuli on Saccadic Trajectories.International journal of environmental research and public health · 2022Review
- Superior Colliculus to VTA pathway controls orienting response and influences social interaction in mice.Nature communications · 2022Article
- The "Primitive Brain Dysfunction" Theory of Autism: The Superior Colliculus Role.Frontiers in integrative neuroscience · 2022Article
- Single-Cell RNA Sequencing Characterizes the Molecular Heterogeneity of the Larval Zebrafish Optic Tectum.Frontiers in molecular neuroscience · 2022Article
- The Brainstem-Informed Autism Framework: Early Life Neurobehavioral Markers.Frontiers in integrative neuroscience · 2021Article
- The influence of subcortical shortcuts on disordered sensory and cognitive processing.Nature reviews. Neuroscience · 2020Review
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
After been exposed to the visual input, in the first year of life, the brain experiences subtle but massive changes apparently crucial for communicative/emotional and social human development. Its lack could be the explanation of the very high prevalence of autism in children with total congenital blindness. The present theory postulates that the superior colliculus is the key structure for such changes for several reasons: it dominates visual behavior during the first months of life; it is ready at birth for complex visual tasks; it has a significant influence on several hemispheric regions; it is the main brain hub that permanently integrates visual and non-visual, external and internal information (bottom-up and top-down respectively); and it owns the enigmatic ability to take non-conscious decisions about where to focus attention. It is also a sentinel that triggers the subcortical mechanisms which drive
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.