Evidence map›Paper›PMID 30686932›Full record

ArticleGreen chemistry : an international journal and green chemistry resource : GC2019

Automated and Accelerated Synthesis of Indole Derivatives on a Nano-Scale.

Shabnam Shaabani, Ruixue Xu, Maryam Ahmadianmoghaddam, Li Gao, Martin Stahorsky, Joe Olechno, Richard Ellson, Michael Kossenjans, Victoria Helan, Alexander Dömling

Abstract read
In one paragraph

Article in Green chemistry : an international journal and green chemistry resource : GC, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
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  4. Review
  5. Review
  6. 'Chemistry at the speed of sound': automated 1536-well nanoscale synthesis of 16 scaffolds in parallel.Green chemistry : an international journal and green chemistry resource : GC · 2023
    Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Advancement in Organic Synthesis through High Throughput Experimentation.Chemistry methods : new approaches to solving problems in chemistry · 2021
    Article
  13. Article
  14. Article
  15. Automated, Accelerated Nanoscale Synthesis of Iminopyrrolidines.Angewandte Chemie (International ed. in English) · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Shabnam Shaabani *University of Groningen, Department of Drug Design, A. Deusinglaan 1, 9713 AV Groningen, The Netherlands.
Ruixue Xu *University of Groningen, Department of Drug Design, A. Deusinglaan 1, 9713 AV Groningen, The Netherlands.
Maryam AhmadianmoghaddamUniversity of Groningen, Department of Drug Design, A. Deusinglaan 1, 9713 AV Groningen, The Netherlands.
Li GaoUniversity of Groningen, Department of Drug Design, A. Deusinglaan 1, 9713 AV Groningen, The Netherlands.
Martin StahorskyUniversity of Groningen, Department of Drug Design, A. Deusinglaan 1, 9713 AV Groningen, The Netherlands.
Joe OlechnoLabcyte Inc., 170 Rose Orchard Way, San Jose, CA 95134, USA.
Richard EllsonLabcyte Inc., 170 Rose Orchard Way, San Jose, CA 95134, USA.
Michael KossenjansHit Discovery, Discovery Sciences, IMED Biotech Unit, AstraZeneca, Gothenburg, SE-43183 Mölndal, Sweden.
Victoria HelanHit Discovery, Discovery Sciences, IMED Biotech Unit, AstraZeneca, Gothenburg, SE-43183 Mölndal, Sweden.
Alexander DömlingUniversity of Groningen, Department of Drug Design, A. Deusinglaan 1, 9713 AV Groningen, The Netherlands.

Funding

Real-time discovery of inhibitors among billion compounds for preview and downloadR01GM097082 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CAMACHO, CARLOS J. · 2011 to 2020
$2.5M
NIGMS NIH HHS R01 GM097082
6 · The paper itself

Abstract

Automated, miniaturized and accelerated synthesis for efficient property optimization is a formidable challenge for chemistry in the 21

Identifiers

PMID30686932
PMCPMC6342289

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.