Evidence map›Paper›PMID 30686670›Full record

ArticleSurgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery2019

DiaRem2: Incorporating duration of diabetes to improve prediction of diabetes remission after metabolic surgery.

Christopher D Still, Peter Benotti, Tooraj Mirshahi, Adam Cook, G Craig Wood

Abstract read
In one paragraph

Article in Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Observational
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Diabetes remission after bariatric surgery.World journal of diabetes · 2021
    Review
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Christopher D StillObesity Research Institute, Geisinger Clinic, Danville, Pennsylvania.
Peter BenottiObesity Research Institute, Geisinger Clinic, Danville, Pennsylvania.
Tooraj MirshahiWeis Center for Research, Geisinger Clinic, Danville, Pennsylvania.
Adam CookObesity Research Institute, Geisinger Clinic, Danville, Pennsylvania.
G Craig WoodObesity Research Institute, Geisinger Clinic, Danville, Pennsylvania. Electronic address: cwood@geisinger.edu.

Funding

Research BaseP30DK072488 · NIDDK · UNIVERSITY OF MARYLAND BALTIMORE · PI MITCHELL, BRAXTON D, TAYLOR, SIMEON I. · 2005 to 2019
$17.3M
Epigenetic markers of severity in nonalcoholic fatty liver diseaseR01DK107735 · NIDDK · TRANSLATIONAL GENOMICS RESEARCH INST · PI DISTEFANO, JOHANNA K, GERHARD, GLENN S · 2016 to 2020
$3.1M
NIDDK NIH HHS P30 DK072488NIDDK NIH HHS R01 DK107735
6 · The paper itself

Abstract

backgroundDiaRem is a validated tool for predicting the likelihood of type 2 diabetes (T2D) remission after Roux-en-Y gastric bypass (RYGB) surgery.

objectivesThe objective of this study was to determine if the addition of duration of T2D to DiaRem improves its ability to discriminate between patients with or without T2D remission and/or to reclassify presurgery patients into accurate risk groups.

settingAcademic Medical Center.

methodsThis study included patients consented into a prospective registry of Roux-en-Y gastric bypass between July 2009 and November 2015 with known duration of T2D (n = 307). Electronic health record-derived duration of T2D was compared with patient reported duration of T2D in a subset of patients (n = 48). DiaRem2 was created using clinical variables from DiaRem and duration of T2D. Area under the curve and the net reclassification index were used to assess increased performance of DiaRem2.

resultsSelf-reported duration of T2D was highly concordant with electronic health record-derived T2D duration (96% agreement). Early T2D remission occurred in 44% of patients. DiaRem2 included age, hemoglobin A1C, insulin medication use, and duration of T2D. DiaRem2 had a higher area under the curve than DiaRem (.876 versus .850, P = .026), reduced the number of remission risk groups from 5 down to 3, and reclassified patients from intermediate to either high or low remission groups (net reclassification index, P < .0001).

conclusionsDiaRem2 simplifies and improves the accuracy of assessing probability of T2M remission after Roux-en-Y gastric bypass. Self-reported duration of T2D is an acceptable surrogate for T2D duration derived from clinical data.

Indexed as

Gastric BypassRemission InductionDiabetes Mellitus, Type 2FemaleHumansMaleMiddle AgedPredictive Value of TestsDiabetes durationDiabetes remissionRYGB

Identifiers

PMID30686670
PMCPMC6589131

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.