Evidence map›Paper›PMID 30686314›Full record

ArticleBritish journal of anaesthesia2019

Tidal changes in PaO

D C Crockett, J N Cronin, N Bommakanti, R Chen, C E W Hahn, G Hedenstierna, A Larsson, A D Farmery, F Formenti

Open access · hybridAbstract read
In one paragraph

Article in British journal of anaesthesia, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Article
  3. Bedside monitoring of lung volume available for gas exchange.Intensive care medicine experimental · 2021
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

D C CrockettNuffield Division of Anaesthetics, University of Oxford, Oxford, UK. Electronic address: douglas.crockett@ndcn.ox.ac.uk.
J N CroninCentre for Human and Applied Physiological Sciences, King's College, London, UK.
N BommakantiNuffield Division of Anaesthetics, University of Oxford, Oxford, UK; Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA.
R ChenNuffield Division of Anaesthetics, University of Oxford, Oxford, UK.
C E W HahnNuffield Division of Anaesthetics, University of Oxford, Oxford, UK.
G HedenstiernaHedenstierna Laboratory, Department of Medical Sciences, Uppsala University, Uppsala, Sweden.
A LarssonHedenstierna Laboratory, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.
A D FarmeryNuffield Division of Anaesthetics, University of Oxford, Oxford, UK.
F FormentiNuffield Division of Anaesthetics, University of Oxford, Oxford, UK; Centre for Human and Applied Physiological Sciences, King's College, London, UK; Department of Biomechanics, University of Nebraska Omaha, Omaha, NE, USA. Electronic address: federico.formenti@outlook.com.
University of Oxford · GBUppsala University · SEKing's College London · GB

Funding

Department of Health II-AR-0410-12031Department of Health II-LA-0214-20006Medical Research Council MC_PC_17164
6 · The paper itself

Abstract

backgroundTidal recruitment/derecruitment (R/D) of collapsed regions in lung injury has been presumed to cause respiratory oscillations in the partial pressure of arterial oxygen (PaO

methodsFive anaesthetised pigs were studied after surfactant depletion via a saline-lavage model of R/D. The animals were ventilated with a mean fraction of inspired O

resultsDuring tidal ventilation, the expiratory lung collapse increased when I:E <1 [mean (standard deviation) lung collapse=15.7 (8.7)%; P<0.05], but the amplitude of respiratory PaO

conclusionsThis study in a porcine model of collapse-prone lungs did not demonstrate the expected association between PaO

Indexed as

Oxygen ConsumptionRecruitment, NeurophysiologicalAcute Lung InjuryAnimalsBlood Gas AnalysisFemaleMalePulmonary AtelectasisRespiration, ArtificialRespiratory MechanicsSwineTherapeutic IrrigationTidal VolumeTomography, X-Ray Computeddiagnostic imagingdynamic computed tomorgraphylung injurypulmonary atelectasisrespirationventilation

Identifiers

PMID30686314
PMCPMC6354046
OpenAlexW2898807807

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.